A Clinical Study to Evaluate the Efficacy of Pippali Churna with Madhu and Pathyadi Churna with Jirna Guda in the Management of Urdhwaga Amlapitta (Gastroesophageal Reflux Disease)

Comparison of the efficacy of Pippali Churna with Madhu and Pathyadi Churna with Jirna Guda in the management of Urdhwaga Amlapitta with reference to Gastroesophageal Reflux Disease - NIL

Status

Active, not recruiting

Phases

Phase 2Phase 3

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2026/03/107034

Enrollment

Registered

2026-03-30

Start date

Unknown

Completion date

Unknown

Last updated

2026-04-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K219- Gastro-esophageal reflux disease without esophagitis

Interventions

None listed

Eligibility

Inclusion criteria

Inclusion criteria: 1.Patients fulfilling the diagnostic criteria based on classical signs and symptoms of Amlapitta as mentioned in Madhav Nidana chapter 51 verse 2, such as Avipaka meaning indigestion, Klama meaning tiredness, Utklesha meaning nausea, Tiktamlodgara meaning sour and bitter belching, Gaurava meaning heaviness in the body, Hrit Kantha Daha meaning burning sensation in the epigastric region and chest, and Aruchi meaning loss of appetite. 2.Patients in the age group of 18 to 50 years. 3.Patients irrespective of gender, geographical area, religion and economic condition. 4.Patients who are willing to participate in the trial and give written informed consent.

Exclusion criteria

Exclusion criteria: 1.Patients who are known cases of severe conditions such as gastric ulcer. 2.Patients who have undergone any gastric surgery. 3.Patients who are unable to stop steroidal or non steroidal anti inflammatory drugs during the study period. 4.Pregnant women and lactating mothers. 5.Patients diagnosed with carcinoma of the stomach or immunocompromised conditions. 6.Patients having other conditions such as chronic alcoholism leading to increased acidity.

Design outcomes

Primary

Measure	Time frame
To compare the efficacy of Pippali churna with madhu and Pathyadi churna with jirna guda in the management of Urdhwaga Amlapitta with refrence to GERD.Timepoint: Assessment will be done at baseline before starting treatment, on day 7, day 14 and day 21 during the course of treatment.	—

Secondary

Measure	Time frame
1. To review Amlapitta according to Ayurved and Modern. 2. To Review literature of Pippali churna with madhu & Pathyadi churna with jirna guda. 3. To evaluate efficacy of Pippali churna with madhu in the management of Urdhwaga Amlapitta with refrence to GERD. 4. To evaluate efficacy of Pathyadi churna with jirna guda in the management of Urdhwaga Amlapitta with refrence to GERD. 5. To observe any adverse drug reaction in both formulations. (Pippali churna with madhu & Pathyadi churna with jirna guda ).Timepoint: 21 days	—

Measure

Time frame

1. To review Amlapitta according to Ayurved and Modern. 2. To Review literature of Pippali churna with madhu & Pathyadi churna with jirna guda. 3. To evaluate efficacy of Pippali churna with madhu in the management of Urdhwaga Amlapitta with refrence to GERD. 4. To evaluate efficacy of Pathyadi churna with jirna guda in the management of Urdhwaga Amlapitta with refrence to GERD. 5. To observe any adverse drug reaction in both formulations. (Pippali churna with madhu & Pathyadi churna with jirna guda ).Timepoint: 21 days

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Countries

India

Contacts

Public ContactDrSandeep Thaknath Shinde

PMTS Ayurved College Shevgaon

vd.sandeepshinde@gmail.com9405766631

Outcome results