Health Condition 1: P073- Preterm [premature] newborn [other]
Conditions
Interventions
Intervention1: Nucleotide Enriched Human Milk Fortifier: Preterm infants will receive human milk fortified with a nucleotide-enriched human milk fortifier. The fortifier will be added to human milk in
Sponsors
NICE Hospital For Women, Newborn And Children Hyderabad
Eligibility
Inclusion criteria
Inclusion criteria: Preterm neonates less than thirty four weeks gestation. Birth weight less than two kilograms. Receiving enteral feeding with human milk. Parental informed consent obtained.
Exclusion criteria
Exclusion criteria: Neonates with major congenital gastrointestinal malformations Neonates with severe congenital heart disease or other life threatening congenital anomalies. Neonates with severe intrauterine growth restriction (IUGR) [defined as birth weight ,with abnormal doppler [AEDF/REDF]. Neonates deemed unlikely to survive or for whom exclusive parenteral nutrition is anticipated. Neonates who had undergone surgery under anesthesia.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Growth Accretion: Weight gain measured in grams per kilogram per day from birth until discharge or 36 weeks postmenstrual age whichever is earlier.Timepoint: From birth until discharge or 36 weeks postmenstrual age whichever is earlier | — |
Secondary
| Measure | Time frame |
|---|---|
| Incidence of feeding intolerance.Timepoint: During hospitalization from initiation of feeds until discharge.;Time to achieve full enteral feeds defined as one hundred fifty milliliters per kilogram per day.Timepoint: During NICU stay until achievement of full feeds.;Time to regain birth weight.Timepoint: From birth until regain of birth weight.;Other growth parametersTimepoint: Weekly measurements of head circumference and length. ;Incidence of necrotizing enterocolitis stage two or higher and late onset sepsis.Timepoint: During hospitalization. | — |
Countries
India
Contacts
Public ContactDr Vinay V Kulkarni
NICE Hospital For Women, Newborn And Children
Outcome results
None listed