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A study comparing the Effects of Metformin and Oral contraceptive pills on chronic inflammatory markers and Adipokines in Polycystic ovary syndrome patients

Effect of Metformin and Oral contraceptive pills on chronic inflammatory markers and Adipokines in Polycystic ovary syndrome patients-A Comparative study. - NIL

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2026/03/107005
Enrollment
100
Registered
2026-03-27
Start date
Unknown
Completion date
Unknown
Last updated
2026-04-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: E282- Polycystic ovarian syndrome

Interventions

Intervention1: Tab Ethinyl Estradiol 35 mcg with Cyproterone acetate 2mg once a day after meal: Tab Ethinyl Estradiol 35 mcg with Cyproterone acetate 2mg will be given for 6 months Control Interventio

Sponsors

All India Institute Of Medical Sciences Bilaspur
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1.Patients diagnosed with PCOS according to modified Rotterdam 2003 Criteria 2.Females of age between18- 45 years.

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

MeasureTime frame
Measuring the change in mean inflammatory markers and adipokines level from baseline to 24 weeks in the metformin group as compared to OCPs groupTimepoint: Measuring the change in mean inflammatory markers and adipokines level from baseline to 24 weeks in the metformin group as compared to OCPs group—

Secondary

MeasureTime frame
1.Mean change from baseline in insulin resistance, BMI and lipid profile at 24 weeks of treatment and also among two groups. 2.Mean change from the baseline in gonadotropins, total testosterone and free testosterone index levels at 24 weeks of treatment and also among the two groups. Timepoint: 24 weeks—

Countries

India

Contacts

Public ContactDr Preyander Singh Thakur

All India Institute of Medical sciences,Bilaspur (Himachal Pradesh)

preyander.thakur@gmail.com7807408966

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: May 1, 2026