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A Clinical Trial to study the effects of two drugs, dexamethasone and methylprednisolone in patients with Sudden sensorineural hearing loss

Comparison of Efficacy of Intratympanic Methylprednisolone & Intratympanic Dexamethasone in the treatment of Sudden Sensorineural Hearing loss- A Randomized controlled trial - Nil

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2026/03/106970
Enrollment
46
Registered
2026-03-27
Start date
Unknown
Completion date
Unknown
Last updated
2026-04-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: H839- Unspecified disease of inner ear

Interventions

Intervention1: Intratympanic methylprednisolone injection: Intratympanic Methylprednisolone Injections will be given in patients with sudden sensorineural hearing loss Control Intervention1: Intratymp

Sponsors

AIIMS Vijaypur Jammu
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1. Patient diagnosed with Sudden SNHL,Sudden sensorineural hearing loss is most often defined as sensorineural hearing loss of 30dB or greater over at least three contiguous audiometric frequencies presenting within duration of 6 months. Patients aged 18 60 years.

Exclusion criteria

Exclusion criteria: Patient with conductive or mixed hearing loss Patient with presence of pre-existing otologic conditions such as chronic otitis media, Meniere s disease, or other inner ear pathologies. Patients with a documented allergy or hypersensitivity to methylprednisolone, dexamethasone, or other corticosteroids.

Design outcomes

Primary

MeasureTime frame
To assess the improvement in Pure Tone Audiometry after treatment with intratympanic methylprednisolone versus dexamethasone.Timepoint: To assess the improvement in Pure Tone Audiometry after treatment with intratympanic methylprednisolone versus dexamethasone at baseline, 1 week, 1 month and 6 months—

Secondary

MeasureTime frame
NilTimepoint: Nil—

Countries

India

Contacts

Public ContactMuskan Rao

All India Institute of Medical Sciences, Jammu

darwin.kaushal@aiimsjammu.edu.in8003647999

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: May 1, 2026