Preventing Excess Bleeding in Childbirth Among Women with Low Platelet Count Using Tranexamic Acid

Role of prophylactic use of Tranexamic Acid in preventing PPH in patients with thrombocytopenia - nil

Status

Active, not recruiting

Phases

Phase 4

Study type

Observational

Source

CTRI

Registry ID

CTRI/2026/03/106960

Enrollment

Registered

2026-03-27

Start date

Unknown

Completion date

Unknown

Last updated

2026-04-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O280- Abnormal hematological finding onantenatal screening of mother

Interventions

Intervention1: Nil: Nil Intervention2: Tranexamic Acid: At the time of induction or onset of labor TXA will be started, 1 g IV 8 hourly till delivery.

Eligibility

Inclusion criteria

Inclusion criteria: Antenatal patients Platelet count less than 1 lakh Willing to participate in the study

Exclusion criteria

Exclusion criteria: Not willing to participate, patient with known tranexamic acid allergy, congenital bleeding disorder, ongoing anticoagulant therapy, active Ca.

Design outcomes

Primary

Measure	Time frame
Reduction in blood loss during childbirth in patients with thrombocytopeniaTimepoint: At baseline and 24 hours	—

Secondary

Measure	Time frame
Reduction Fall in HB or Hct 24 hrs after delivery Reduced need for use of other methods to manage PPH like mechanical or uterotonic drugs or surgical procedures Reduced need for requirement of blood transfusion.Timepoint: After 24 hours	—

Countries

India

Contacts

Public ContactDr Sanyukta kale

AIIMS New Delhi

drneha.ucms@gmail.com8802502597

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: May 1, 2026