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Effect of injection ondansetron through vein to prevent low blood pressure happening after spinal anaesthesia in old age patients

Efficacy of prophylactic intravenous administration of ondansetron for prevention of spinal anaesthesia induced hypotension in elderly patients: a prospective randomised double blind study - NIL

Status
Active, not recruiting
Phases
Phase 2
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2026/03/106953
Enrollment
160
Registered
2026-03-27
Start date
Unknown
Completion date
Unknown
Last updated
2026-04-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O- Medical and Surgical

Interventions

Intervention1: Group A: Ondansetron Group: Individual receiving inj ondansetron 8 mg diluted in 10 mL of 0.9% sodium chloride (NaCl) will be infused 1 minutes and 5 minutes before spinal anaesthesia.

Sponsors

Dibyarup Das
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: ASA grade 1 and 2, elderly patients age more than 60 years, giving informed written consent, undergoing elective surgical procedure requiring spinal anaesthesia

Exclusion criteria

Exclusion criteria: Any contraindication to neuraxial anaesthesia, patients with sever cardiorespiratory disease, neurological disorder, endocrine disorder, psychiatric problem, patients who will not given valid consent, surgical procedures taking more than 2 hours

Design outcomes

Primary

MeasureTime frame
Proportion of patients who experience hypotension during surgery defined as systolic blood pressure less than 80% of base line or below 90 mm of HgTimepoint: will be recorded every 3 minutes for 30 minute after giving spinal anaesthesia

Secondary

MeasureTime frame
The incidence of bradycardia, use of vasopressors & changes in blood pressure & heart rateTimepoint: will be recorded every 3 minutes for 30 minute after giving spinal anaesthesia

Countries

India

Contacts

Public ContactDr Dibyarup Das

Midnapore Medical College and Hospital

drnilambar@gmail.com9883258680

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: May 1, 2026