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Comparison of two pain-relief medicine combinations for reducing pain and swelling after wisdom tooth removal.

Evaluation of the effectiveness of biphasic versus monophasic aceclofenac, paracetamol and serratiopeptidase following mandibular third molar extraction - A randomised controlled trial. - NIL

Status
Active, not recruiting
Phases
Phase 3Phase 4
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2026/03/106950
Enrollment
200
Registered
2026-03-27
Start date
Unknown
Completion date
Unknown
Last updated
2026-04-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: M269- Dentofacial anomaly, unspecified

Interventions

Intervention1: Bi layered combination of aceclofenac paracetamol and serratiopeptidase: Bi layered combination of aceclofenac (100mg) paracetamol (325mg) and serratiopeptidase (10 mg ) will be given t

Sponsors

Dr DY Patil Dental College and Hospital
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1. Indicated for mandibular third molar extraction. 2. Patients willing to provide informed consent and comply with follow-up.

Exclusion criteria

Exclusion criteria: 1. Known allergy or intolerance to study drug components. 2. Medically compromised patients 3. Pregnant or lactating females. 4. History of chronic NSAID or steroid use.

Design outcomes

Primary

MeasureTime frame
GI discomfort on administration of both combinations post operatively.Timepoint: GI discomfort on administration of both combinations post operatively, on day 1 2 and 3

Secondary

MeasureTime frame
Swelling on administration of both combinations post operatively.Timepoint: On day 1 and 3;Pain reduction on administration of both combinations post operatively.Timepoint: On day 1 and 3

Countries

India

Contacts

Public ContactDr Abhilasha Lad

Dr DY Patil Dental College and Hospital, Dr DY Patil Vidyapeeth, Pimpri, Pune 411018.

sonal.shah@dpu.edu.in9833459822

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: May 1, 2026