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A study to assess and compare two types of laser light treatment for gum disease and their impact on gum health

Effect of dual-wavelength laser periodontal therapy with photobiomodulation on clinical outcomes and gingival crevicular fluid stromal derived factor-1alpha levels: A randomized controlled trail - NIL

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2026/03/106932
Enrollment
33
Registered
2026-03-27
Start date
Unknown
Completion date
Unknown
Last updated
2026-04-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K053- Chronic periodontitis

Interventions

Intervention1: Laser-assisted flap surgery and Photobiomodulation therapy will be performed using 650 nm diode laser : Patients with Stage II or Stage III, Grade B periodontitis will be undergoing fla

Sponsors

Dr. B Manohar Reddy
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1.Patients diagnosed with stage-II and III and Grade-B periodontitis (as per the 2017 classification.) 2.Probing pocket depth (PPD) greater than 5 mm 3.Clinical attachment level (CAL) greater than 3 mm in at least three teeth.

Exclusion criteria

Exclusion criteria: 1.Patients with systemic diseases or conditions affecting periodontal healing (e.g., diabetes mellitus, immunocompromised states). 2.Use of antibiotics, anti-inflammatory drugs, or corticosteroids within the previous 3 months. 3.Current smokers or tobacco users in any form. 4.Pregnant or lactating women. 5.Patients with a history of periodontal surgery at the selected site within the past 6 months

Design outcomes

Primary

MeasureTime frame
changes in clinical parameters Probing Pocket Depth (PPD) and Clinical Attachment Level (CAL) Timepoint: baseline, 3rd month, and 6th month—

Secondary

MeasureTime frame
Evaluation of changes in gingival crevicular fluid Stromal-Derived Factor-1alpha (SDF-1alpha) levelsTimepoint: baseline, 2nd week, and 6th week;Soft tissue healing assessed using Landry Healing Index (HI)Timepoint: 7th day and 21st day;Postoperative pain assessment using Visual Analog Scale (VAS)Timepoint: 0-day and 7th day.—

Countries

India

Contacts

Public ContactDr Mohan Kumar P

Vishnu Dental College

anilkumar.perio@vdc.edu.in9677209549

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: May 1, 2026