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Efficacy and safety of Lox 5% lidocaine patch compared with intravenous paracetamol in elective caesarean section patients.

A PROSPECTIVE COMPARATIVE RANDOMIZED CONTROL STUDY OF POST OPERATIVE PAIN MANAGEMENT IN ELECTIVE CESAREAN SECTION USING 5% LIGNOCAINE PATCH VS PARACETAMOL INFUSION - NIL

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2026/03/106915
Enrollment
80
Registered
2026-03-25
Start date
Unknown
Completion date
Unknown
Last updated
2026-03-30

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O82- Encounter for cesarean delivery without indication

Interventions

Intervention1: 5% Lignocaine Patch: Patients in this group will have a 5% Lidocaine transdermal patch applied 1cm above the surgical incision site immediately after surgery. The patch will be left in

Sponsors

Joseph Nixon Mavely
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Patients between 18 to 40 years of age, belonging to ASA Physical Status I & II, undergoing elective lower segment caesarean section (LSCS) with singleton pregnancies under spinal anaesthesia will be considered eligible

Exclusion criteria

Exclusion criteria: 1. Not willing for the consent 2. History of any previous intraabdominal surgery 3. Known allergy or hypersensitivity to Lignocaine, Paracetamol, or any components of the study drugs. 4. Presence of chronic pain disorders or history of long-term analgesic use. 5. Patients with hepatic or renal dysfunction. 6. Presence of coagulopathy, local skin infection at the patch site, or other contraindications to regional anaesthesia. 7. Patients with intraoperative complications (e.g., conversion to general anaesthesia, excessive bleeding) affecting postoperative pain interpretation. 8. Patients unable to understand or comply with pain scoring systems (e.g., due to language barriers, cognitive impairment, or psychiatric illness).

Design outcomes

Primary

MeasureTime frame
Compare the postoperative analgesic efficacy of a transdermal Lignocaine 5% patch versus intravenous Paracetamol infusion in the immediate postoperative periodTimepoint: 24 hours

Secondary

MeasureTime frame
Higher Maternal Satisfaction, Reduced need for rescue analgesiaTimepoint: First 24 Hours

Countries

India

Contacts

Public ContactDr Gunjan Ashokkumar Badwaik

Datta Meghe Medical College

painkiller_gab@yahoo.co.in9689892039

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Apr 4, 2026