comparision of soft tissue healing of tooth sockets treated with 0.8% hyaluronic acid with normal healing in diabetes mellitus patients

Comparative evaluation of soft tissue healing in extracted tooth socket treated with 0.8 percent Hyaluronic Acid versus control in Type II Diabetes Mellitus-A Randomised Controlled Trial - NIL

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2026/03/106887

Enrollment

Registered

2026-03-25

Start date

Unknown

Completion date

Unknown

Last updated

2026-03-30

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K055- Other periodontal diseases

Interventions

Intervention1: Hyaluronic Acid: After extraction, followed by debridement, a prefilled syringe containing 0.8% hyaluronic acid gel will be loaded in and placed inside the socket and the socket will b

Eligibility

Inclusion criteria

Inclusion criteria: Patients aged from 35 to 60 years. 2. Patients with controlled Type 2 Diabetes Mellitus(HbA1C below 7%) 3. Patient undergoing atleast 2 atraumatic extractions. 4. Patients willing to participate and for follow up

Exclusion criteria

Exclusion criteria: Presence of abscess for the teeth indicated for extraction 2. Patients allergic to Hyaluronic acid 3. Poorly controlled diabetic patient ((HbA1C 8% or higher) 4. Patients with Immunocompromised conditions 5. Patients on anticoagulant and antiplatelet therapy 6. Pregnant/ Lactating women 7. Chronic smokers

Design outcomes

Primary

Measure	Time frame
Soft-tissue healing score (Landry s wound healing index) Measurement: Clinical evaluation + standardised photographs on Day 7,14,21 Standardisation: Same scoring criteria for all sockets. Timepoint: 7th,14th and 21st day	—

Secondary

Measure	Time frame
Wound area Method: Measured with vernier caliper. Pain (VAS score) Method: Patient marks pain level (0 10) on a visual analogue scale. Standardisation: Patients instructed on how to use VAS. Pain (VAS score) Method: Patient marks pain level (0 10) on a visual analogue scale. Standardisation: Patients instructed on how to use VAS. Timepoint: 7th,14th & 21st day	—

Countries

India

Contacts

Public ContactDr Pallavi Shyam Ghodpage

AIIMS Guwahati

pghodpage@gmail.com9836205713

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Apr 4, 2026