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Comparison of laser therapy and autologous blood concentrate for interdental papilla reconstruction

Comparison of Hemolaser Therapy and Injectable-Platelet Rich Fibrin for Interdental Papilla Reconstruction: A Randomized Controlled Non- Inferiority Trial - NIL

Status
Active, not recruiting
Phases
Phase 2Phase 3
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2026/03/106874
Enrollment
70
Registered
2026-03-25
Start date
Unknown
Completion date
Unknown
Last updated
2026-03-30

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K060- Gingival recession

Interventions

Intervention1: Hemolaser therapy: 660nm laser therapy in contact mode onto the deficient interdental papilla before and after microneedling of the site in 2 sittings 7 days apart. Control Intervention

Sponsors

Dr Kavitha K
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1.Systemically healthy patients with age between 18-65 years having Nordland and Tarnow Class I or II interdental papilla loss. 2.Stable periodontal status (FMPS & FMBS less than 10 percentage and probing pocket depth less than 4mm). 3.Radiographically, the distance between contact point (CP) to alveolar crest should be less than 6mm. 4.Sites devoid of active caries 5.Non-smokers and non-tobacco users. 6.Willing to provide informed consent and available for follow-up appointments.

Exclusion criteria

Exclusion criteria: 1.Pregnant or lactating women. 2.Use of medications interfering with tissue repair of any other serious health issues 3.Patients having open contact. 4.Patients undergoing orthodontic treatment

Design outcomes

Primary

MeasureTime frame
Change in interdental papilla height between 2 groupsTimepoint: 1 week, 1 month and 3 months

Secondary

MeasureTime frame
Change in black triangle heightTimepoint: 1 week, 1 month and 3 months;Change in Probing pocket depth (PPD)Timepoint: 3 months;Post operative pain (No. of analgesic tablets consumed)Timepoint: 1 week;Patient esthetic satisfaction- VAS (Visual Analogue Scale)scoreTimepoint: 1 month, 3 months

Countries

India

Contacts

Public ContactDr Baiju RM

Government Dental College, Kottayam

baijurm@gmail.com9447279605

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Apr 4, 2026