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Comparison between two types of Platelet Rich Fibrin effectiveness

A Prospective Randomized Control Single-Blinded Clinical Trial to Compare Post-Extraction Healing Outcomes Following Mandibular Third Molar Surgery Using Injectable Platelet-Rich Fibrin (I-Prf) and Titanium-Prepared Platelet-Rich Fibrin (T-Prf) - NIL

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2026/03/106858
Enrollment
42
Registered
2026-03-24
Start date
Unknown
Completion date
Unknown
Last updated
2026-03-30

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

Intervention1: Surgical Removal of Impacted mandibular third molar: The duration of the procedure will be approximately 60 to 90 minutes and with follow up on post operative day 1,3,7 and after 6 mont

Sponsors

Dr. Adrish Misra
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: All the patients of age 18-50 ASA Class I patients Presence of impacted mandibular third molar classified as Pell and Gregory Class I or II and Position A

Exclusion criteria

Exclusion criteria: Immunocompromised patients or patients with systemic disease Patients smoking or chewing tobacco Pregnant and lactating females

Design outcomes

Primary

MeasureTime frame
1.Bone Density 2.Socket bone healingTimepoint: Immediately(day after surgery) 6 months follow up—

Secondary

MeasureTime frame
1.Post operative pain 2.Facial swelling 3.Soft tissue healing at extraction site 4.Maximum mouth openingTimepoint: Day 1 (baseline) Day 3 Day 7—

Countries

India

Contacts

Public ContactDr Sanjeev Tomar

Institute of Dental Studies and Technologies

drgauravmittal@rediffmail.com7042166299

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Apr 4, 2026