Maggot Debridement Therapy versus normal care for the prevention of amputation in diabetic foot ulcers: A pilot study

Maggot Debridement Therapy versus standard care for the prevention of amputation in diabetic foot ulcers: A pilot study - NIL

Status

Active, not recruiting

Phases

Phase 1Phase 2

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2026/03/106856

Enrollment

Registered

2026-03-24

Start date

Unknown

Completion date

Unknown

Last updated

2026-03-30

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: E115- Type 2 diabetes mellitus with circulatory complications

Interventions

None listed

Eligibility

Inclusion criteria

Inclusion criteria: Known diabetes Type 1 or 2 with a chronic non-healing Diabetic foot ulcer for more than 4 weeks in duration. University of Texas classification of DFU, Grade 1 and 2, and Stage A & B Triphasic and Biphasic arterial flow on Doppler in the affected limb (DPA or PTA). ABPI more than 0.8 Pt suffering numbness and loss of pain sensation at the wound (sensory peripheral neuropathy) Written informed consent obtained

Exclusion criteria

Exclusion criteria: No biphasic or monophasic flow or absent pulses ABI INDEX less than 0.8 Ulcers belonging to University of Texas Classification Grade 3 or 4, Stage C & D. Chronic Kidney Disease /or Acute Kidney Failure Allergy to Maggots or intolerance to MDT materials or dressings. Diabetic Emergencies like DKA/HHC cases Septicemic cases

Design outcomes

Primary

Measure	Time frame
To evaluate the clinical efficacy and feasibility of Maggot Debridement Therapy (MDT) compared to Standard of Care (SOC) in preventing lower-limb amputations and promoting wound bed preparation in patients suffering from chronic diabetic foot ulcers (DFUs) Primary ObjectiveTimepoint: To evaluate the clinical efficacy and feasibility of Maggot Debridement Therapy (MDT) compared to Standard of Care (SOC) in preventing lower-limb amputations and promoting wound bed preparation in patients suffering from chronic diabetic foot ulcers (DFUs) Primary Objective	—

Measure

Time frame

To evaluate the clinical efficacy and feasibility of Maggot Debridement Therapy (MDT) compared to Standard of Care (SOC) in preventing lower-limb amputations and promoting wound bed preparation in patients suffering from chronic diabetic foot ulcers (DFUs) Primary ObjectiveTimepoint: To evaluate the clinical efficacy and feasibility of Maggot Debridement Therapy (MDT) compared to Standard of Care (SOC) in preventing lower-limb amputations and promoting wound bed preparation in patients suffering from chronic diabetic foot ulcers (DFUs) Primary Objective

—

Secondary

Measure	Time frame
Rate of appearence of healthy grannulation ntissueTimepoint: 1 week	—

Countries

India

Contacts

Public ContactDr Namrata Tripathi

AIIMS, NEW DELHI

drnamratatripathi@hotmail.com09934399192

Outcome results