Health Condition 1: O- Medical and Surgical
Conditions
Interventions
Intervention1: Tab duloxetine: Patients were randomly assigned into two groups Group A received duloxetine 30 mg the night before surgery and 30 mg two hours before surgery All doses were given orally
Sponsors
keerthan k p
Eligibility
Inclusion criteria
Inclusion criteria: Adult patients undergoing laparoscopic cholecystectomy. Patients belonging to ASA grade 1 and 2 BMI 18- 24 kg/m2
Exclusion criteria
Exclusion criteria: Liver or renal dysfunction Daily corticosteroid use History of duloxetine allergy Patients with cognitive psychological or communication disorders Patient with uncontrolled DM HTN and IHD Pregnant or nursing women
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Time to First Analgesic Requirement postoperativelyTimepoint: 2 hours, 4 hours, 8 hours, 12 hours, and 24 hours postoperatively | — |
Secondary
| Measure | Time frame |
|---|---|
| Assessment of pressor response during intubation after administration of duloxetine preoperativelyTimepoint: 1 minute, 3 minutes, 5 minutes, 10 minutes, & 15 minutes after the induction of anesthesia;Comparison of postoperative shoulder pain in two groupsTimepoint: 2 hours, 4 hours, 8 hours, 12 hours 24 hours postoperatively;Assessment of Adverse Events: ponv, shivering, urinary retention, sedation, & other adverse events if anyTimepoint: 2 hours, 4 hours, 8 hours, 12 hours 24 hours postoperatively | — |
Countries
India
Contacts
Public ContactDr keerthan k p
Shri B.M. Patil Medical College, Hospital & Research Centre Vijayapur, Karnataka
Outcome results
None listed