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A novel non-invasive tool to guide high flow oxygen support in critically ill children

A novel non-invasive tool to guide High Flow Nasal Cannula respiratory support in critically ill children

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
CTRI
Registry ID
CTRI/2026/03/106830
Enrollment
143
Registered
2026-03-24
Start date
Unknown
Completion date
Unknown
Last updated
2026-03-30

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: J989- Respiratory disorder, unspecified

Interventions

Intervention1: Nil: Nil

Sponsors

Amrita Institute of Medical Sciences
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: All paediatric patients admitted in PICU initiated on High flow nasal cannula and whose parents consent for participation will be included

Exclusion criteria

Exclusion criteria: Patients with hemodynamic instability or GCS less than 12 or tracheostomy or nasal bleed or CSF rhinorrhoea or facial deformity or patients cycled between HFNC and NIV or Patients in whom HFNC abruptly stopped for major surgical intervention requiring invasive ventilatory support

Design outcomes

Primary

MeasureTime frame
Prediction of HFNC therapy outcome, defined as success ( successful weaning off HFNC) or failure of HFNC support (based on need for escalation to non invasive or invasive ventilation).Timepoint: At predefined assessment intervals after initiation of HFNC, namely 2, 4, 6, 12, 18, 24, and 48 hours, and daily thereafter and at the point of clinical decision making such as escalation to non invasive or invasive ventilation or successful weaning off from HFNC

Secondary

MeasureTime frame
Description of clinical spectrum of HFNC use in PICU including indications patient characteristics duration of HFNC & overall clinical course during PICU stayTimepoint: Across PICU stay including at initiation of HFNC & assessments at 2, 4, 6, 12, 18, 24, & 48 hours & daily thereafter till end of HFNC therapy along with final outcomes such as duration of HFNC & total length of PICU stay

Countries

India

Contacts

Public ContactDr Veena Raghunathan

Amrita Institute of Medical Sciences, Amrita Vishwa Vidyapeetham

drvraghunathan@gmail.com9871221112

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Apr 4, 2026