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Effect of Tooth Polishing Between Teeth and the Role of Remineralizing Agents in Enamel Protection

Evaluation of Enamel Surface Characteristics And Remineralization Potential of Commercially Available Agents Following Interproximal Reduction: An In Vivo Study - ERIPR

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2026/03/106818
Enrollment
36
Registered
2026-03-24
Start date
Unknown
Completion date
Unknown
Last updated
2026-03-30

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

Intervention1: nil: nil Control Intervention1: nil: nil

Sponsors

DARSHNA KUMARI
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Patients with Angle Class I malocclusion or Angle class II Division 1 malocclusion with aligned arches requiring premolar extractions as part of orthodontic treatment. Patients requiring interproximal reduction (IPR) as part of treatment. Teeth free from caries, restorations, cracks, or developmental defects. Patients with good general and oral health. Patients who provide informed consent.

Exclusion criteria

Exclusion criteria: Teeth with caries, restorations, enamel hypoplasia, or cracks. Patients with systemic diseases affecting mineral metabolism. Patients with poor oral hygiene or active periodontal disease. Patients with a history of previous orthodontic treatment. Patients using fluoride or remineralizing agents other than those provided in the study. Patients unwilling to participate or provide consent.

Design outcomes

Primary

MeasureTime frame
To assess the remineralization potential of nano-hydroxyapatite (nHAp),sodium fluoride (NaF) varnish, casein phosphopeptide-amorphous calcium phosphate (CPP-ACP) on enamel surfaces following interproximal reduction. Timepoint: To assess the remineralization potential of nano-hydroxyapatite (nHAp),sodium fluoride (NaF) varnish, casein phosphopeptide-amorphous calcium phosphate (CPP-ACP) on enamel surfaces following interproximal reduction.

Secondary

MeasureTime frame
To assess the remineralization potential of nano-hydroxyapatite (nHAp),sodium fluoride (NaF) varnish, casein phosphopeptide-amorphous calcium phosphate (CPP-ACP) on enamel surfaces following interproximal reduction and to compare the effectiveness of nHAp, NaF varnish, and CPP-ACP in terms of Enamel surface roughness, Enamel microhardness, Elemental composition (calcium-to-phosphorus ratio)Timepoint: To assess the remineralization potential of nano-hydroxyapatite (nHAp),sodium fluoride (NaF) varnish, casein phosphopeptide-amorphous calcium phosphate (CPP-ACP) on enamel surfaces following interproximal reduction and to compare the effectiveness of nHAp, NaF varnish, and CPP-ACP in terms of Enamel surface roughness, Enamel microhardness, Elemental composition (calcium-to-phosphorus ratio)

Countries

India

Contacts

Public ContactDR EENAL BHAMBRI

SURENDERA DENTAL COLLEGE AND RESEARCH INSTITUTE SRIGANGANAGAR, RAJASTHAN 335001

dreenal700@gmail.com8769829700

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Apr 4, 2026