A study to compare pain relief after shoulder surgery using a nerve block with ropivacaine alone versus ropivacaine with dexmedetomidine.

A comparative study of efficacy of ultrasound guided interscalene brachial plexus block with 0.2% ropivacaine vs 0.2% ropivacaine with dexmedetomidine on postoperative analgesia in patients undergoing shoulder surgery. - NIL

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2026/03/106806

Enrollment

Registered

2026-03-24

Start date

Unknown

Completion date

Unknown

Last updated

2026-04-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: M759- Shoulder lesion, unspecified

Interventions

Intervention1: Ropivacaine: 9ml of 0.2% Ropivacaine with 1 ml of NS was administered for ultrasound-guided IBPB Control Intervention1: dexmedetomidine: 9ml of 0.2% ropivacaine + 0.5 mcg/kg dexmedetom

Eligibility

Inclusion criteria

Inclusion criteria: 1. ASA grade I or II fit patients. 2. Ages between 18 and 65 years 3. Patients undergoing upper shoulder surgeries under General anesthesia. 4. Hemodynamically stable patients with all routine investigations within normal limits . 5. Patients who are not on any cardiac related drugs. 6. Availability of written informed consent from concerned patient.

Exclusion criteria

Exclusion criteria: 1. Patients not willing to get enrolled in this study. 2. Patients with ASA physical status III or more. 3. Patients below 18 years and above 65 years of age. 4. Patients posted for emergency procedures. 5. Patients with uncontrolled systemic disorders like diabetes mellitus, heart disease, chronic hypertension, pulmonary disorders, etc. 6. Patients with bleeding or coagulation disorders. 7. Patients with known allergies to the study drugs.

Design outcomes

Primary

Measure	Time frame
To compare the analgesic efficacy of 0.2% ropivacaine versus 0.2% ropivacaine with dexmedetomidine in ultrasound guided interscalene brachial plexus block in patients undergoing shoulder surgeriesTimepoint: After administration of the block, comparison between the two groups of onset and duration of sensory and motor blockade, duration of analgesia and time to rescue analgesia will be assessed at baseline, after injection of study drug, at 5 mins, 10 mins, 15 mins, 30 mins and at the end of surgery.	—

Measure

Time frame

To compare the analgesic efficacy of 0.2% ropivacaine versus 0.2% ropivacaine with dexmedetomidine in ultrasound guided interscalene brachial plexus block in patients undergoing shoulder surgeriesTimepoint: After administration of the block, comparison between the two groups of onset and duration of sensory and motor blockade, duration of analgesia and time to rescue analgesia will be assessed at baseline, after injection of study drug, at 5 mins, 10 mins, 15 mins, 30 mins and at the end of surgery.

—

Secondary

Measure	Time frame
To compare postoperative analgesia between the two groups using pain scores & requirement of rescue analgesiaTimepoint: Duration of analgesia will be assessed postoperatively once the effect of block wears off & time to rescue analgesia will be assessed at 2 hours after surgery & then hourly up to 24 hours postoperatively	—

Countries

India

Contacts

Public ContactSHILPA SARANG KORE

DR.D.Y.PATIL MEDICAL COLLEGE,PUNE,PIMPRI

shilpasale@gmail.com9767002436

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: May 1, 2026