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Effect of Ghee Application on Tooth Bacteria

The Effect of Clarified Butter (Ghee) On Streptococcus Mutans levels in plaque biofilm A Randomized Controlled Clinical Study - NIL

Status
Active, not recruiting
Phases
Phase 2
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2026/03/106802
Enrollment
40
Registered
2026-03-24
Start date
Unknown
Completion date
Unknown
Last updated
2026-03-30

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

Intervention1: CLARIFIED BUTTER (GHEE): Topical application of clarified butter (ghee) 5 ml applied on all tooth surfaces using a disposable applicator brush twice daily for 30 days along with routin

Sponsors

Dr Batheja Sahil
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1 Participants who can comprehend and provide consent to participate 2 Minimum 20 natural teeth present 3 Presence of visible plaque with moderate oral hygiene status (Silness and Loe Index) 4 Not having any known medical history and no pregnancy 5 Participant has not received oral prophylaxis in the last 3 months. 6 Willingness to follow study protocol

Exclusion criteria

Exclusion criteria: 1 Patients with active periodontal infection 2 History of antibiotic use or use of mouth rinses in the last 1 month. 3 Lactose intolerance and Participants who have been exposed to dairy products or ghee and have a known allergy 4 Participants Practicing a Vegan diet 5 Periodontal or orthodontic treatment in progress. 6 Smokers or tobacco users or individuals with oral lesions 7 Participants using oral rinse regularly

Design outcomes

Primary

MeasureTime frame
Quantitative change in Streptococcus mutans count in plaque biofilm (CFU per ml) Timepoint: Baseline (Day 0) Day 30 (end of intervention)

Secondary

MeasureTime frame
Change in Plaque Index scores (Silness and L e Index) Participant reported acceptability and tolerability Timepoint: Baseline Day 30 (end of intervention)

Countries

India

Contacts

Public ContactDr Vanamala N

DAPM RV Dental College Bangalore

vanamalan.rvdc@rvei.edu.in9880010512

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Apr 4, 2026