Comparative study of hyperbaric Levobupivacaine(0.5%) versus hyperbaric Ropivacaine(0.75%) in elective lower limb Orthopaedic surgeries under spinal anaesthesia

Randomised double blind comparative study of hyperbaric Levobupivacaine(0.5%) versus hyperbaric Ropivacaine(0.75%) in elective lower limb Orthopaedic surgeries under spinal anaesthesia - NIL

Status

Active, not recruiting

Phases

Phase 1

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2026/03/106798

Enrollment

Registered

2026-03-24

Start date

Unknown

Completion date

Unknown

Last updated

2026-03-30

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O- Medical and Surgical Health Condition 2: S829- Unspecified fracture of lower leg

Interventions

Intervention1: 0.75 percent Ropivacaine: 0.75 percent Ropivacaine in lower limb orthopaedic surgeries under spinal anaesthesia Control Intervention1: 0.5 percent Levobupivacaine: Intrathecal administr

Eligibility

Inclusion criteria

Inclusion criteria: 1.Adult patients (18-65 years) undergoing elective lower limb orthopaedic surgeries under spinal anaesthesia 2.ASA I/II. 3.Those providing informed consent. 4.Patients not contraindicated for spinal anaesthesia

Exclusion criteria

Exclusion criteria: 1.Patients with contraindications for spinal anaesthesia(e.g.coagulopathy,infection, neurological disease). 2.Severe cardiovascular/respiratory/renal/hepatic impairment,pregnancy/lactation,psychiatric conditions. 3.American Society of Anesthesiologist Grade III and IV patients. 4.Infection at local site of spinal anaesthesia 5.Patients with hemodynamic instability. 6.Patients with allergy to or history of hypersensitivity to local anaesthetics. 7.Emergency surgeries.

Design outcomes

Primary

Measure	Time frame
Onset,Duration of sensory and motor blockTimepoint: Level of sensory and motor block will be assessed every 5 min till maximum block,every 15min intraoperatively,every 30 min postoperatively till complete regression	—

Secondary

Measure	Time frame
NILTimepoint: NIL	—

Countries

India

Contacts

Public ContactDr Avinash Sukhdev Deshmukh

Mahatma Gandhi Institute of Medical Sciences,Sevagram,Wardha

nikhilyadav@mgims.ac.in8308513091

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Apr 4, 2026