Compare the efficacy between amisulpride and dexamethasone in post operative nausea and combating

To Compare the Efficacy and Safety of Intravenous Amisulpride Against Dexamethasone in Post-Surgical Patients to Prevent Post-Operative Nausea and Vomiting (PONV): A Randomized, Controlled, Prospective Study - Nil

Status

Active, not recruiting

Phases

Phase 3Phase 4

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2026/03/106726

Enrollment

120

Registered

2026-03-23

Start date

Unknown

Completion date

Unknown

Last updated

2026-03-30

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: R112- Nausea with vomiting, unspecified

Interventions

Intervention1: administration of intravenous antiemetic drugs: The intervention in this study consists of administration of intravenous antiemetic drugs, where patients in one group receive intravenou

Eligibility

Inclusion criteria

Inclusion criteria: : Surgery to last at least 1 hour :Overnight stay :General anaesthesia :ASA I&II :At least one of the following Apfel et al s risk factors for PONV: Female sex Non-smoking status A prior history of PONV or motion sickness Being expected to receive postoperative opioid analgesia

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

Measure	Time frame
Proportion of patients achieving complete response (no nausea, no vomiting, and no requirement for rescue antiemetic) within the first 24 hours after surgery.Timepoint: 0 2 hours postoperatively 2 6 hours postoperatively 6 24 hours postoperatively	—

Secondary

Measure	Time frame
NilTimepoint: Nil	—

Countries

India

Contacts

Public ContactReena Kankotiya

Sumandeep vidhyapeeth

Reenakankotiya008@gmail.com8779455374

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Apr 4, 2026