Reduction of signs of gum disease after application of a gel which releases oxygen and a type of LASER light energy in the treatment of patients suffering from gum disease

Comparative Evaluation of Adjunctive Use of Oxygen-Releasing Gel and Combo-Coherence Pocket Debridement and Their Combination with Scaling and Root Planing Versus Scaling and Root Planing Alone In Stage-III and Stage-IV Periodontitis: A Split-Mouth Randomized clinical controlled trial - NIL

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2026/03/106674

Enrollment

Registered

2026-03-20

Start date

Unknown

Completion date

Unknown

Last updated

2026-03-30

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K053- Chronic periodontitis

Interventions

Intervention1: Scaling and Root Planing followed by Oxygen Releasing gel application: All The Procedures Will Be The Same As Those Performed In The Comparator Group. This Will Be Followed By Local App

Eligibility

Inclusion criteria

Inclusion criteria: Stage-III or Stage-IV periodontitis Presence of a minimum of 20 natural teeth with at least 5 natural teeth in each quadrant periodontal pockets more than or equal to 4 mm in depth on at least one of the six sites examined per tooth with involvement of a minimum of two teeth in different quadrants ASA I ASA II subjects non smokers Subjects who have provided written informed consent

Exclusion criteria

Exclusion criteria: History of periodontal therapy within the last 6 months. Subjects with a history of antibiotic therapy within the last 3 months. Teeth with more than grade III mobility. Subjects who smoke or use any form of tobacco products. Subjects who are Pregnant or lactating. Subjects with a known history of allergy or hypersensitivity to any of the constituents of Blue-M gel. Subjects with a known history of allergy or hypersensitivity to any of the constituents of local anesthesia.

Design outcomes

Primary

Measure	Time frame
Changes in probing periodontal pocket depths and changes in periodontal clinical attachment levelsTimepoint: Baseline, 3 months and 6 months post-treatment	—

Secondary

Measure	Time frame
Chnages in Plaque indexTimepoint: Baseline, 3 months and 6 months post-treatment;Chnages in gingival indexTimepoint: Baseline, 3 months and 6 months post-treatment;Changes in marginal tissue recessionTimepoint: Baseline, 3 months and 6 months post-treatment	—

Countries

India

Contacts

Public ContactDr Omkumar Baghele

Maharashtra Institute of Dental Sciences and Research, Latur.

drakankshaperio@gmail.com9359818546

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Apr 4, 2026