Skip to content

Study on Effectiveness of Cognitive Behavioral Therapy and Imagery Rescripting as psychotherapeutic interventions in treating chronic depression

Efficacy of Cognitive Behavioral Therapy and Imagery Rescripting in People with Chronic Depression: A Randomized Controlled Study - NIL

Status
Active, not recruiting
Phases
Phase 2
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2026/03/106672
Enrollment
56
Registered
2026-03-20
Start date
Unknown
Completion date
Unknown
Last updated
2026-03-30

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: F341- Dysthymic disorder

Interventions

Intervention1: Imagery Rescripting: Imagery Rescripting (ImRs) is a therapeutic technique and a standalone intervention that helps individuals mentally revisit distressing memories and modify the imag

Sponsors

Devika Nair
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Individuals who meet the criteria for persistent depressive disorder, as per the DSM 5-TR (screened using DIAMOND, and PDS), who have been symptomatic for at least majority of the last 2 years Individuals fluent and conversant in English, with High school level reading and comprehension ability Individuals with first onset of depression during peripartum period. Individuals with mild to marked symptoms of depression based on screening by DIAMOND, and who receive scores greater than 8 in HDRS and 14 in BDI (indicating mild depression or greater severity) Individuals who are stabilized on pharmacotherapy for at least 4 weeks or not on pharmacotherapy at the start of the trial

Exclusion criteria

Exclusion criteria: 1 Individuals who have current comorbid Axis I disorders which may interfere with their ability to actively participate in therapy, such as, but not limited to, organic mental disorders, psychotic disorders, bipolar disorder, obsessive compulsive disorder, posttraumatic stress disorder, and complex- post traumatic stress disorder. 2 Individuals with substance use disorders (except tobacco use disorder) 3 Individuals with active suicidal ideations or risk of self harm 4 Individuals with moderate to severe personality disorder 5 Individuals with Chronic/life threatening physical illnesses such as autoimmune conditions, diagnosed pain disorders, neurological disorders etc. 6 Individuals who have undergone structured therapy for depression in the past 3 months

Design outcomes

Primary

MeasureTime frame
Severity of Depression ScoresTimepoint: Baseline Mid-Intervention Post-intervention 3-month follow up

Secondary

MeasureTime frame
Psychological Flexibility Attention Control Emotional Processing Shame and Guilt Early Maladaptive Schemas Interpersonal Sensitivity Helpful aspects of Therapy Timepoint: Baseline Mid-Intervention Post-intervention 3 month follow up

Countries

India

Contacts

Public ContactDr M Manjula

National Institute of Mental Health and Neuro Sciences

drmanjula71@gmail.com9632603597

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Apr 4, 2026