Health Condition 1: F422- Mixed obsessional thoughts and acts
Conditions
Interventions
Intervention1: Arm 1: SSRIs alone: Standard daily dosages of SSRIs not exceeding as mentioned below:
1. Escitalopram 20-80 mg or
2. Fluoxetine 20-120 mg
3. Clonazepam 1 mg or
4. Lorazepam 2 mg
Inter
75 trains of 2s and 20Hz with 14s ITI given at 100% of foot RMT
3000 pulses/session
4 sessions per day for 5 days
total 20 sessions
Sponsors
Investigator Initiated Trial
Eligibility
Inclusion criteria
Inclusion criteria: a. Patients and their legally accepted relatives who provide consent to participate in the study. b. Diagnosis of OCD as per ICD10. c. Patients whose YBOCS is at or above 14. d. Patients on any previous medication for OCD will be shifted to SSRI-only regimen after one week wash-out period prior to recruiting.
Exclusion criteria
Exclusion criteria: a. Nonconsenting patients or their relatives b. Patients with significant suicidality c. Patients with substance dependence and substance withdrawal symptoms d. Pregnant women e. Patients declared unfit after screening for electromagnetic field compatibility f. Patients with severe and unstable medical comorbidities.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Change in the absolute Yale Brown Obsessive Compulsive ScaleTimepoint: Day 1, Day 5, Day 30, Day 90, Day 180 | — |
Secondary
| Measure | Time frame |
|---|---|
| 1. Clinical Global Impression (CGI) Timepoint: Day 1, Day 5, Day 30, Day 90, Day 180;2. World Health Organization Disability Assessment Schedule (WHODAS) 2.0Timepoint: Day 1, Day 5, Day 30, Day 90, Day 180 | — |
Countries
India
Contacts
Public ContactDr Aswin Kumar M
Asha Neuromodulation Clinics
Outcome results
None listed