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Comparative Evaluation of Sugammadex versus Neostigmine for Reversal of Neuromuscular Blockade in Adult Surgical Patients Under General Anesthesia: Effects on Recovery Profile and Safety Outcomes

Comparative evaluation of sugammadex versus neostigmine for reversal of neuromuscular blockade in patients undergoing surgery under general anesthesia

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
CTRI
Registry ID
CTRI/2026/03/106549
Enrollment
20
Registered
2026-03-19
Start date
Unknown
Completion date
Unknown
Last updated
2026-03-30

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

Intervention1: Nil: Nil Control Intervention1: Sugammadex versus Neostigmine: Both are reversal agents used for reversing patients undergoing surgery under general anesthesia.

Sponsors

Shri Ram Murti Smarak Institute of Medical Sciences
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: ASA I,II,III Duration of surgery more than or equal to 2 hours Body mass index 18-25 kg/m2 Informed consent

Exclusion criteria

Exclusion criteria: Patients with significant preexisting pulmonary,renal or neuromuscular disorders Pregnant women Previous history of nausea and vomiting Previous history of hypersensitivityto study medications

Design outcomes

Primary

MeasureTime frame
faster reversal in patients where sugammadex has been used as reversal agentTimepoint: faster reversal in patients where sugammadex has been used as reversal agent—

Secondary

MeasureTime frame
Lesser postoperative complications Better hemodynamic parameters Early discharge from postoperative discharge unitTimepoint:—

Countries

India

Contacts

Public ContactDR Riya Sarkar

Shri Ram Murti Smarak Institute of Medical Sciences

rsarkar3105@gmail.com9641667141

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Apr 4, 2026