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Effect of drinking a carbohydrate drink before surgery on blood sugar control and recovery after gastrointestinal cancer surgery

Effect of pre-operative Carbohydrate loading on post-operative Insulin Resistance in patients undergoing surgery for Gastrointestinal malignancy: A Randomized Controlled Trial - NIL

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2026/03/106539
Enrollment
80
Registered
2026-03-19
Start date
Unknown
Completion date
Unknown
Last updated
2026-03-30

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K35-K38- Diseases of appendix Health Condition 2: K20-K31- Diseases of esophagus, stomach and duodenum Health Condition 3: K70-K77- Diseases of liver Health Condition 4: K80-K87- Disorders of gallbladder, biliary tract and pancreas Health Condition 5: K55-K64- Other diseases of intestines Health Condition 6: K90-K95- Other diseases of the digestive system

Interventions

Intervention1: Oral Carbohydrate Drink: OCL group (oral carbohydrate loading) will receive 400 ml of clear carbohydrate drink (maltose dextrin,12.5g of carbohydrate per 100ml) at 10pm the day before s

Sponsors

Department of Surgical Gastroenterology
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Patients admitted for elective surgery for GI malignancy in Surgical Gastroenterology department in AIIMS Patna Age more than 18 years If the disease turns out to be metastatic at some later point in the study

Exclusion criteria

Exclusion criteria: Emergency surgeries Metastatic disease Patients presenting with Gastric outlet obstruction, Dysphagia, Intestinal Obstruction Known cases of chronic diseases such as uncontrolled Diabetes Mellitus(HbA1c more than or equal to 6.5%), Chronic Liver Disease, Chronic Kidney Disease

Design outcomes

Primary

MeasureTime frame
To compare the effect of oral carbohydrate loading and preoperative prolonged fasting over the Insulin resistance seen post operatively in patients undergoing surgery for Gastrointestinal malignancies using the HOMA-IR calculatorTimepoint: Pre-operatively, Post operative day 1, Post operative Day 3—

Secondary

MeasureTime frame
The post operative complications on the basis of Clavein-Dindo classificationTimepoint: Pre-operatively, Post operative day 1, Post operative Day 3;The post operative time to discharge based on fulfillment of the following criteria: A. Passage of stools/ Functional moving stoma B. Tolerating soft diet C. No or minimal tolerable abdominal pain D. Drain removed/ Drain output less than 50ml Timepoint: Pre-operatively, Post operative day 1, Post operative Day 3;The post operative CRP in patients undergoing surgery for Gastrointestinal malignanciesTimepoint: Pre-operatively, Post operative day 1, Post operative Day 3—

Countries

India

Contacts

Public ContactKunal Kalani

All India Institute of Medical Sciences (AIIMS), Patna

kislay.kant@gmail.com9958615755

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Apr 4, 2026