Health Condition 1: I10-I16- Hypertensive diseases Health Condition 2: I49- Other cardiac arrhythmias
Conditions
Interventions
Intervention1: Calcium channel blockers: Any one out of Amlodipine 2.5 mg to 10 mg
Cilnidipine 10 mg to 20 mg
Nifedipine 10 mg to 60 mg
(All doses- based on clinical judgement
continued as long as indicated as per prevalent guidelines for blood pressure control or till adverse event warrants cessation of therapy)
Intervention2: Nil: Nil
Intervention3: Nil: Nil
Intervention4
continued as long as indicated as per prevalent guidelines for heart rate control or till adverse event warrants cessation of therapy)
Control Intervention1: Other medicines for hypertension: Any one
continued as long as indicated as per prevalent guidelines for blood pressure control or till adverse event warrants cessation of therapy)
Control Intervention2: Other medicines for tachyarrhythmias o
continued as long as indicated as per prevalent guidelines for heart rate control or till adverse event warrants cessation of therapy)
Sponsors
BANARAS HINDU UNIVERSITY
Eligibility
Inclusion criteria
Inclusion criteria: Elderly patients who are more than/equal to 60 years of age and diagnosed with hypertension or tachycardia/tachyarrhythmia and started on CCBs or other anti hypertensives or started on CCBs or other rate controlling agents and who give consent to participate in the study
Exclusion criteria
Exclusion criteria: Patients with below mentioned conditions shall be excluded Associated dementia Established neuropsychiatric disorders at baseline Serious illnesses like myocardial infarction or stroke which may deem recruitment in study unfavorable as per treating geriatrician Serious acute illness requiring hospitalization Significant hearing or speech or vision loss which makes communication impossible
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Behavioral changesTimepoint: at baseline 1 month 3 month 6 month and 12 month | — |
Secondary
| Measure | Time frame |
|---|---|
| Motor disordersTimepoint: at baseline 1 month 3 month 6 month and 12 month;Quality of lifeTimepoint: at baseline 1 month 3 month 6 month and 12 month;Cognitive statusTimepoint: at baseline 1 month 3 month 6 month and 12 month;Depression statusTimepoint: at baseline 1 month 3 month 6 month and 12 month;Functional statusTimepoint: at baseline 1 month 3 month 6 month and 12 month;Adverse eventsTimepoint: at baseline 1 month 3 month 6 month and 12 month;Motion sensor data- exploratoryTimepoint: at baseline 1 month 3 month 6 month and 12 month- optional | — |
Countries
India
Contacts
Public ContactSankha Shubhra Chakrabarti
Institute of Medical Sciences Banaras Hindu University
Outcome results
None listed