Health Condition 1: K721- Chronic hepatic failure
Conditions
Interventions
Intervention1: Nil: Nil
Intervention2: Nil: Nil
Intervention3: Nil: Nil
Sponsors
KOREA UNIVERSITY COLLEGE OF MEDICINE
Eligibility
Inclusion criteria
Inclusion criteria: ACLF patients who underwent LDLT between 2013 and 2023 Definition of ACLF: A clinical syndrome characterized by acute decompensation in patients with chronic liver disease (typically cirrhosis), accompanied by failure of one or more major organ systems
Exclusion criteria
Exclusion criteria: Patients with fulminant hepatic failure or acute liver failure without underlying chronic liver disease Patients lost to follow-up within 1 year after LDLT Patients with incomplete or insufficient medical records, making data analysis impossible
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Short-term and long-term clinical outcomes of ACLF patients undergoing LDLT and assess its clinical efficacy. Timepoint: Research Planning & IRB Approval: 2 months Data Collection & Analysis: 9 months Results Reporting & Manuscript Writing: 3 months | — |
Secondary
| Measure | Time frame |
|---|---|
| Risk factors identified for futility (defined as death within 3 months post-transplant or in-hospital mortality) in ACLF patients receiving LDLT and to develop predictive models for transplant outcomes.Timepoint: Research Planning & IRB Approval: 2 months Data Collection & Analysis: 9 months Results Reporting & Manuscript Writing: 3 months | — |
Countries
India
Contacts
Public ContactDr Peush Sahni
Max Super Specialty Hospital
Outcome results
None listed