A Study To Compare The Effectiveness Of Dexmedetomidine And Fentanyl By Adding To Levobupivacaine In Patients Undergoing Hand Surgeries

Comparison Of Efficacy Of Dexmedetomidine And Fentanyl As Adjuvant To Levobupivacaine 0.5% In Ultrasound Guided Supraclavicular Brachial Plexus Block In Patients Undergoing Upper Limb Surgeries - A Randomised Clinical Trial - NIL

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2026/03/106409

Enrollment

100

Registered

2026-03-17

Start date

Unknown

Completion date

Unknown

Last updated

2026-03-30

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O- Medical and Surgical

Interventions

Intervention1: ULTRASOUND GUIDED SUPRACLAVICULAR BRACHIAL PLEXUS BLOCK: ULTRASOUND GUIDED SUPRACLAVICULAR BRACHIAL PLEXUS BLOCK IN PATIENTS UNDERGOING UPPER LIMB SURGERIES Control Intervention1: ULTRA

Eligibility

Inclusion criteria

Inclusion criteria: ASA Grade I and II scheduled for elective upper limb surgeies

Exclusion criteria

Exclusion criteria: 1.Patient refusal 2.Local site infections 3.Patients on anticoagulants or bleeding disorders 4.Hypersensitivity to amide group of Local anaesthetic agents and dexmedetomidine. 5.Pre-existing neuropathy or neurological disorders of upper limb autonomic neuropathy /peripheral nerve injury 6.Significant cardiac, hepatic or renal disease 7.Pregnancy and lactation

Design outcomes

Primary

Measure	Time frame
To compare the onset and duration of sensory and motor block between dexmedetomidine and fentanyl as adjuvants to levobupivacaine in ultrasound-guided supraclavicular brachial plexus blockTimepoint: BASELINE, 15 MINUTES,30 MINUTES, 45 MINUTES, 60 MINUTES, 90 MINUTES, 120 MINUTES, 2 HOURS, 4 HOURS,6 HOURS, 8 HOURS, 10 HOURS & 12 HOURS	—

Secondary

Measure	Time frame
To compare duration of post operative analgesia between the two groups.Timepoint: BASELINE, 15 MINUTES,30 MINUTES, 45 MINUTES, 60 MINUTES, 90 MINUTES, 120 MINUTES, 2 HOURS, 4 HOURS,6 HOURS, 8 HOURS, 10 HOURS & 12 HOURS;To compare the adverse effects like bradycardia, tachycardia, hypotension, anaphylaxis, nausea or vomiting between the two groups. Timepoint: BASELINE, 15 MINUTES,30 MINUTES, 45 MINUTES, 60 MINUTES, 90 MINUTES, 120 MINUTES	—

Measure

Time frame

To compare duration of post operative analgesia between the two groups.Timepoint: BASELINE, 15 MINUTES,30 MINUTES, 45 MINUTES, 60 MINUTES, 90 MINUTES, 120 MINUTES, 2 HOURS, 4 HOURS,6 HOURS, 8 HOURS, 10 HOURS & 12 HOURS;To compare the adverse effects like bradycardia, tachycardia, hypotension, anaphylaxis, nausea or vomiting between the two groups. Timepoint: BASELINE, 15 MINUTES,30 MINUTES, 45 MINUTES, 60 MINUTES, 90 MINUTES, 120 MINUTES

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Countries

India

Contacts

Public ContactDr Yumnam Arunkumar Singh

Regional Institute of Medical Sciences

yaks48@yahoo.com9862282518

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Apr 4, 2026