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A Comparison of Two Lasers for Treating Skin Pigmentation Problems

COMPARATIVE STUDY OF Q SWITCHED ND YAG LASER VS PICOSECOND LASER FOR TREATMENT OF VARIOUS PIGMENTARY DISORDERS USING A SPLIT LESION DESIGN - NIL

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2026/03/106326
Enrollment
36
Registered
2026-03-16
Start date
Unknown
Completion date
Unknown
Last updated
2026-03-30

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: L812- Freckles Health Condition 2: L813- Cafe au lait spots Health Condition 3: L814- Other melanin hyperpigmentation Health Condition 4: L818- Other specified disorders of pigmentation Health Condition 5: L819- Disorder of pigmentation, unspecified

Interventions

Intervention1: Q Switched Nd:YAG laser: Comparison of efficacy and safety of picosecond Nd:YAG vs Q Switched Nd:YAG laser Study duration is 1.5 years Control Intervention1: Picosecond Nd:YAG laser: Co

Sponsors

Department of Dermatology and Venereology and Leprosy
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Patients above 18 years. Presence of one or more hyperpigmentary disorders amenable to Nd:YAG laser therapy as per the literature. No treatment taken for the condition (topical/ oral/ procedural) in the last 6 months. Written informed consent to participate in the study and comply with the treatment schedule, follow-up appointments, and post-treatment care instructions.

Exclusion criteria

Exclusion criteria: Unwillingness to consent to participate in the study. Pregnancy and Lactation. Increased Sensitivity to Light. Scars or Florid inflammation of the tattooed skin or area immediately surrounding it. Treatment taken for the pigmentary condition in the last 6 months. Active Skin Conditions: No Active cutaneous infections (bacterial, viral, or fungal) in or near the treatment area. No History of recurrent herpes simplex virus infection in the treatment area, unless prophylactic antiviral therapy is administered. No Active disease with Koebnerization such as lichen planus pigmentosus, Riehl s melanosis, etc. Concomitant treatment for the pigmentary condition except sunscreen.

Design outcomes

Primary

MeasureTime frame
Picosecond Nd:YAG laser may perform better than Q Switched Nd:YAG in terms of safety and efficacyTimepoint: 4 weeks—

Secondary

MeasureTime frame
NILTimepoint:—

Countries

India

Contacts

Public ContactAmogh Kirtane

Rajiv Gandhi Medical College and Chhatrapati Shivaji Maharaj Hospital

drpradnyarjoshi@gmail.com8108735566

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Apr 4, 2026