A study to compare two medicines named Sugammadex and Neostigmine used to reverse muscle relaxation after general anaesthesia. Also their effect of nausea and vomiting after surgery, will be studied.

Comparison of the effect of the Neuro Muscular reversal agents, sugammadex and neostigmine on postoperative nausea and vomiting in patients undergoing surgeries under general anaesthesia - NIL

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2026/03/106322

Enrollment

104

Registered

2026-03-16

Start date

Unknown

Completion date

Unknown

Last updated

2026-03-30

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K00-K95- Diseases of the digestive system

Interventions

Intervention1: Injection Sugammadex 2mg/kg intravenous will be administered to reverse the effect of injection Vecuronium induced neuromuscular blockage .: Incidence and severity of Post operative Na

Eligibility

Inclusion criteria

Inclusion criteria: Either gender. Patients under ASA grade I, II. Patients scheduled for surgeries to be performed under general anaesthesia. Patients willing to sign written informed consent. Patients ready to comply with perioperative fasting guidelines and protocols.

Exclusion criteria

Exclusion criteria: Patients with grossly impaired cardio-respiratory, hepatic, and renal function. Patients with known allergy any of the study drugs. Patient experienced significant desaturation during induction

Design outcomes

Primary

Measure	Time frame
To compare the incidence and severity of Post Operative Nausea And vomiting.Timepoint: Immediately after surgery 1 hour after surgery 6 hour after surgery 12 hour after surgery 24 hour after surgery	—

Secondary

Measure	Time frame
To compare the need for rescue anti emetics. To monitor adverse event if any. Timepoint: Immediately after surgery 1 hour after surgery 6 hour after surgery 12 hour after surgery 24 hour after surgery	—

Countries

India

Contacts

Public ContactDr Vrajkumar Maheshwari

Parul Institute of Medical Sciences and Research

dr.a.m.chhaya@gmail.com9824233654

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Apr 4, 2026