Health Condition 1: O- Medical and Surgical
Conditions
Sponsors
Subharti Medical College
NAMITA SINGH
Eligibility
Inclusion criteria
Inclusion criteria: 1.Patients with prolonged mechanically ventilated (more than 48hours). 2.All ICU patients who met the criteria to start the weaning process as hemodynamic stability, pH 7.35 to 7.45, PaO2 less than 60mm Hg while breathing with an FiO2 0.4(PaO2:FiO2 less than 200), Positive end-expiratory pressure (PEEP) 5 TO 8cm H2O, tidal volume (TV) more than 5mL/kg, RSBI less than 105 breath/min/L, 3.Patients were fully conscious and cooperative, and secretion management, no electrolyte imbalance 4. No laryngeal edema
Exclusion criteria
Exclusion criteria: 1.Age less than 18years 2.History of neuromuscular diseases, 3.Diaphragmic anatomical malformation of the, 4.Using muscle paralyzing agent during ventilation, 5.Hemodynamic instability
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| 1. To assess diaphragmatic excursion (DE) using M-mode ultrasonography prior to extubation. 2. To assess diaphragmatic thickening fraction (DTF) using B-mode ultrasonography prior to extubation. 3. To compare ultrasound-derived diaphragmatic parameters between patients who have successful extubation and those who experience extubation failure.Timepoint: At intubation, at the time of extubation, after 48 hours of extubation. | — |
Secondary
| Measure | Time frame |
|---|---|
| 1. To determine optimal cutoff values for diaphragmatic excursion and thickening fraction that predict extubation success with high sensitivity and specificity. 2. To correlate diaphragmatic ultrasound findings with standard clinical predictors of weaning such as the Rapid Shallow Breathing Index (RSBI), tidal volume, and results of the spontaneous breathing trial (SBT).Timepoint: At intubation, at the time of extubation, after 48 hours of extubation. | — |
Countries
India
Contacts
Public ContactDR VASUNDHERA TYAGI
Subharti Medical College
Outcome results
None listed