Health Condition 1: S026- Fracture of mandible Health Condition 2: S026- Fracture of mandible
Conditions
Interventions
Intervention1: Local administration of 1000 mg Amoxicillin powder mixed with Advanced Platelet-Rich Fibrin: 10 ml blood collected from patient
A-PRF prepared using PRF centrifugation
1000 mg Amoxici
Sponsors
Krishna Vishwa Vidyapeeth Karad
Eligibility
Inclusion criteria
Inclusion criteria: Patients aged 18 60 years presenting with maxillofacial trauma involving fractures of the dentate segment of the mandible (angle to angle) will be included in the study. Patients with comminuted, compound, or displaced mandibular fractures who are planned for open reduction and internal fixation and who are willing to participate and provide written informed consent will also be included
Exclusion criteria
Exclusion criteria: Patients with condylar fractures of the mandible, fractures that are already infected at the time of presentation (showing granulation tissue or pus discharge), and immunocompromised individuals will be excluded from the study. Additionally, patients who are allergic to Amoxicillin or those not willing to participate will not be included.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Presence of Post-Operative Surgical Site InfectionTimepoint: Immediate post-operative period 1 week 3 weeks 3 months | — |
Secondary
| Measure | Time frame |
|---|---|
| secondary outcomes of this study are post-operative pain measured using the Visual Analogue Scale, wound healing assessed using the Landry wound healing index, and microbial culture and sensitivity testing in cases of infectionTimepoint: Immediate post-operative period 1 week 3 weeks 3 months | — |
Countries
India
Contacts
Public ContactDr Hitesh Dibbe
School of Dental sciences,Krishna Vishwa Vidyapeeth, Karad
Outcome results
None listed