A Clinical Study Comparing EDTA and Ozonated olive oil Effects on rotary instruments, Treatment Time and Pain

Comparative Evaluation of Ozonated Olive Oil and EDTA as Lubricants and their Impact on Instrumentation Time, Postoperative Pain and File Morphology during Pulpectomy: A Randomized Controlled Trial - NIL

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2026/03/106156

Enrollment

Registered

2026-03-13

Start date

Unknown

Completion date

Unknown

Last updated

2026-03-30

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K040- Pulpitis Health Condition 2: K041- Necrosis of pulp

Interventions

Intervention1: Ozonated Olive Oil: Ozonated olive oil used as an intracanal lubricant during pulpectomy, approximately 0.5 1 mL introduced into each root canal using a disposable syringe during rotary

Eligibility

Inclusion criteria

Inclusion criteria: 1.Healthy cooperative children aged 4-8 years 2.Mandibular primary molars with irreversible pulpitis devoid of any other diseased teeth in that quadrant that bothers the patient 3.No history of analgesic use 12 hours prior to pulpectomy

Exclusion criteria

Exclusion criteria: 1.Uncooperative children 2.Children with systemic illness 3.Teeth with clinical and radiographic contraindications for pulpectomy

Design outcomes

Primary

Measure	Time frame
Instrumentation time Timepoint: assessed in minutes at the same day using stop watch from the beginning of rotary instrumentation till the end of preparation	—

Secondary

Measure	Time frame
Post operative painTimepoint: 6 hours, 12 hours, 1st day, 3rd day and 7h day postoperatively;File Morphology evaluation under Scanned Electron Microsc0pyTimepoint: each rotary file after using for every 5 teeth	—

Countries

India

Contacts

Public ContactDr Jayalakshmi Pandranki

GITAM Dental College and Hospital

mds.deepthi@gmail.com9912860194

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Apr 4, 2026