To study the effect of oil application on weight loss in preterm neonates during first 10 days of life

Open label Randomized Controlled Trial Comparing postnatal Weight Loss in Preterm Neonates (28-33+6 weeks ) With and Without Topical Coconut Oil Application During the First 10 Days of Life - NIL

Status

Active, not recruiting

Phases

Phase 2Phase 3

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2026/03/106155

Enrollment

124

Registered

2026-03-13

Start date

Unknown

Completion date

Unknown

Last updated

2026-03-30

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O- Medical and Surgical

Interventions

Intervention1: Topical coconut oil application: Parachute coconut oil will be applied once a day 2 ml/kg will be taken and will be applied over baby without massage from face below without scalp afte

Eligibility

Inclusion criteria

Inclusion criteria: All neonates between 28 to 33 weeks 6 days of gestational age , admitted at less than or at 6 Hour of life

Exclusion criteria

Exclusion criteria: Major life- threatening congenital malformations, major chromosomal anomalies Contraindication to massage like dislocations, fractures. Fetal hydrops Congenital diseases of skin associated with skin breach or denudation of skin precluding oil application Neonates with pre-existing skin infection. Parents who refuse to give consent

Design outcomes

Primary

Measure	Time frame
To determine the difference in the mean gram weight loss during the first 10 days of life between the coconut oil application group and the no oil application group in preterm neonates 28-33+6 weeks gestational age Timepoint: To determine the difference in the mean gram weight loss during the first 10 days of life between the coconut oil application group and the no oil application group in preterm neonates 28-33+6 weeks gestational age	—

Measure

Time frame

To determine the difference in the mean gram weight loss during the first 10 days of life between the coconut oil application group and the no oil application group in preterm neonates 28-33+6 weeks gestational age Timepoint: To determine the difference in the mean gram weight loss during the first 10 days of life between the coconut oil application group and the no oil application group in preterm neonates 28-33+6 weeks gestational age

—

Secondary

Measure	Time frame
To compare the rate of weight gain after day 10 of life between coconut oil and non- oil application group till discharge To assess skin-related adverse effects (e.g., erythema, infection, peeling) associated with coconut oil use. To compare episodes of sepsis between coconut oil and non- oil application group. To determine the episodes of hypothermia between coconut oil and non- oil application group. Timepoint: at day of life 10 and at discharge	—

Measure

Time frame

To compare the rate of weight gain after day 10 of life between coconut oil and non- oil application group till discharge To assess skin-related adverse effects (e.g., erythema, infection, peeling) associated with coconut oil use. To compare episodes of sepsis between coconut oil and non- oil application group. To determine the episodes of hypothermia between coconut oil and non- oil application group. Timepoint: at day of life 10 and at discharge

—

Countries

India

Contacts

Public ContactDr Kasula Prathyush Reddy

Bharati Vidyapeeth (Deemed to be University) Medical College, Pune

malshenandini@gmail.com9822850716

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Apr 4, 2026