Treatment of Short-Sightedness (Kittapaarvai) in Children using Siddha Medicine

An Open-Label, Single-Arm Clinical Trial for the Management of Myopia (Kittapaarvai) in Children attending the Outpatient Department of Ayothidoss Pandithar Hospital, National Institute of Siddha with Karisalai Karpa Chooranam (Internal), Ponnanganni Thylam (External) along with Varmam Therapy - NIL

Status

Active, not recruiting

Phases

Phase 2

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2026/03/106135

Enrollment

Registered

2026-03-13

Start date

Unknown

Completion date

Unknown

Last updated

2026-03-30

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: H521- Myopia

Interventions

Intervention1: Karisalai Karpa Chooranam (Internal): Karisalai Karpa Chooranam will be administered orally. Pediatric dose will be calculated using Clark s rule. The calculated dose will be given twic

Eligibility

Inclusion criteria

Inclusion criteria: Clinical diagnosis of simple myopia. Refractive error ranging from minus 0.50 to minus 6.0 diopters in either eye.

Exclusion criteria

Exclusion criteria: Presence of other refractive errors such as hypermetropia or astigmatism as the primary diagnosis. High myopia greater than minus 6.0 diopters in either eye. Any ocular pathology other than developmental or simple myopia. History of ocular surgery. Participation in another clinical trial within the last 30 days. Known hypersensitivity to the trial medication.

Design outcomes

Primary

Measure	Time frame
Reduction in spherical equivalent refractive error ( SER in diopters)Timepoint: Day 0 (Baseline) and Day 48 (End of treatment)	—

Secondary

Measure	Time frame
Asthenopic Symptom score reduction Proportionate Change in visual acuity (logMAR scale)Timepoint: Day 0, Day 24, Day 48	—

Countries

India

Contacts

Public ContactDr K Vennila

National Institute of Siddha

gvennils@gmail.com9789093986

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Apr 4, 2026