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To compare drug nalbuphine and fentanyl which is better in patients who underwent abdomen surgery and are in icu post surgery

Effectiveness of analgesia between nalbuphine and fentanyl in postoperative patients who underwent Laparotomy a randomized single blinded controlled trial - NIL

Status
Active, not recruiting
Phases
Phase 3
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2026/03/106097
Enrollment
100
Registered
2026-03-13
Start date
Unknown
Completion date
Unknown
Last updated
2026-03-30

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K566- Other and unspecified intestinal obstruction

Interventions

Intervention1: Nalbuphine: Nalbuphine Infusion will be started 0.1mg/kg/hr , IV route in icu post OT , pt is monitored for pain in every 2hr interval for 24 hrs Control Intervention1: Fentanyl: Fentan

Sponsors

Dr Harsh P Chutke
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1 Age more than 18 years 2 Male or Female gender 3 ASA i or ii or iii 4 Patients undergoing elective/emergency laparotomy surgeries surgeries and coming to Surgical ICU for observation or for further management with MV support

Exclusion criteria

Exclusion criteria: 1 Patient refusal 2 Severe systemic illness , ASA iv 3 Patients on chronic opioid use 4 Intraoperative epidural or regional blocks 5 Allergy or hypersensitivity to drugs 6 Patients require prolonged ventilation ie 24 hrs

Design outcomes

Primary

MeasureTime frame
Compare the effectiveness of analgesia by seeing time taken to start first rescue analgesiaTimepoint: 0,2,4,6,8,10,12,14,16,18,20,22,24 hrs

Secondary

MeasureTime frame
Time taken for extubation after stoppage of sedationTimepoint: 0,2,4,6,8,10,12,14,16,18,20,22,24 hrs

Countries

India

Contacts

Public ContactDr Harsh P Chutke

Institute of Medical Sciences and SUM hospital

anitabehera@soa.ac.in9032660550

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Apr 4, 2026