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study of safety of sugammadex vs neostigmine

A comparative study of efficacy and safety of sugammadex and neostigmine for reversal of vecuronium induced neuromuscular blockade - S&N

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2026/03/106070
Enrollment
50
Registered
2026-03-12
Start date
Unknown
Completion date
Unknown
Last updated
2026-03-30

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K806- Calculus of gallbladder and bile duct with cholecystitis

Interventions

Intervention1: Neostigmine: Neostigmine is traditionally used for reversal of neuromuscular blockade but has limitations such as slow onset and autonomic side effects like bradycardia, bronchospasm, a

Sponsors

B.J.Medical College,Ahmedabad.
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: ASA Class I-IV Scheduled for elective surgery under general anaesthesia requiring endotracheal intubation consent for surgery

Exclusion criteria

Exclusion criteria: Difficult airwy, Known or suspected Neuromuscular disorders, Pregnant and lactating women, Women of child bearing age using hormonal contraception, Severe Renal and Liver dysfunction,Major systemic illness,Known or suspected malignant hyperthermia.

Design outcomes

Primary

MeasureTime frame
To compare efficacy and safety of sugammadex and neostigmine for reversal of vecuronium induced neuromuscular blockadeTimepoint: after 0,15,30,60 min of reversal agents—

Secondary

MeasureTime frame
To study the hemodynamic stability and observe adverse effects of reversal agentsTimepoint: after 0,15,30,60 min of reversal agents—

Countries

India

Contacts

Public ContactDrSeema Gandhi

B.J.Medical College,Ahmedabad

drseemagandhi@gmail.com9426373192

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Apr 4, 2026