Effect of adding dexmedetomidine to ropivacaine for ultrasound guided lateral femoral cutaneous nerve block for postoperative pain relief in split skin graft donor site surgery.

A randomized controlled trial comparing ropivacaine with and without dexmedetomidine for ultrasound-guided lateral femoral cutaneous nerve block. - LFCN-DEX Trial

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2026/03/106067

Enrollment

Registered

2026-03-12

Start date

Unknown

Completion date

Unknown

Last updated

2026-03-30

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: T818- Other complications of procedures,not elsewhere classified

Interventions

Intervention1: Ropivacaine only: Ultrasound-guided lateral femoral cutaneous nerve block using 0.25% ropivacaine (10 mL) Control Intervention1: Ropivacaine + dexmedetomidine: Ultrasound-guided lateral

Eligibility

Inclusion criteria

Inclusion criteria: Patients aged 18 to 65 years undergoing split skin graft surgery under anesthesia. Patients belonging to ASA physical status I or II. Patients willing to participate and provide written informed consent.

Exclusion criteria

Exclusion criteria: Patient refusal. Known allergy to local anesthetics or dexmedetomidine. Infection at the injection site. Coagulopathy or bleeding disorders. Severe hepatic or renal disease. Pregnancy. Patients on chronic opioid therapy.

Design outcomes

Primary

Measure	Time frame
Postoperative pain intensity measured using Visual Analog ScaleTimepoint: 1 hour, 2 hours, 4 hours, 6 hours, 12 hours and 24 hours postoperatively.	—

Secondary

Measure	Time frame
Time to first rescue analgesiaTimepoint: Within first 24 hours postoperatively	—

Countries

India

Contacts

Public ContactDr Sakshi Singh

Jhalawar Medical College and Associated Hospitals

dr.sakshi29122016@gmail.com7460819259

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Apr 4, 2026