Comparison of Diclofenac and Ketoprofen pain patches for relief of pain after C-section delivery.

Comparative study of efficacy of Diclofenac and ketoprofen transdermal patches for postoperative pain relief in post LSCS patients. - NIL

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2026/03/106054

Enrollment

108

Registered

2026-03-12

Start date

Unknown

Completion date

Unknown

Last updated

2026-03-30

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O750- Maternal distress during labor anddelivery

Interventions

Intervention1: Diclofenac Sodium transdermal patch: After delivery of the baby, Group D, the Diclofenac Sodium 100 mg transdermal patch, will be applied in the right arm deltoid region for 24 hours po

Eligibility

Inclusion criteria

Inclusion criteria: Patients scheduled for elective or emergency lower segment cesarean section under subarachnoid blockade. ASA grade II

Exclusion criteria

Exclusion criteria: 1. Duration of surgery beyond 90 minutes having intra-op complications. 2. Failed spinal and inadequate spinal anesthesia. Previous hypersensitivity to NSAIDs or any other drugs. 3. High-risk pregnancy with any previous cardiac, respiratory, renal, and liver disease or any coagulation disorders. 4.Patient requiring opioid for rescue analgesia.

Design outcomes

Primary

Measure	Time frame
To compare efficacy of diclofenac and ketoprofen transdermal patch for post operative pain relief in post lower segment cesarean section patientsTimepoint: For the first 24 hours post delivery. at 0 minutes, 30 minutes, 1 hour, 2 hours, 4 hours, 6 hours, 8 hours, 12 hours, 16 hours, 20 hours, 24 hours.	—

Secondary

Measure	Time frame
To compare the hemodynamic parameters (HR, SBP, DBP, MBP, SPO2) intraoperatively & postoperatively.Timepoint: Intraoperative hemodynamic parameters will be assessed at baseline, 2 min, 4 min, 6 min, 8 min, 10 min, 12 min, 14 min, 16 min, 18 min, 20 min, & every 10 min afterwards. Postoperative hemodynamic parameters will be assessed after delivery for the first 24 hours at baseline, 2 hours, 4 hours, 8 hours, 12 hours, 16 hours, 20 hours, & 24 hours.;Any adverse drug reaction between the groups. Timepoint: any complications after delivery and application of patch till 24 hours postoperatively.	—

Measure

Time frame

To compare the hemodynamic parameters (HR, SBP, DBP, MBP, SPO2) intraoperatively & postoperatively.Timepoint: Intraoperative hemodynamic parameters will be assessed at baseline, 2 min, 4 min, 6 min, 8 min, 10 min, 12 min, 14 min, 16 min, 18 min, 20 min, & every 10 min afterwards. Postoperative hemodynamic parameters will be assessed after delivery for the first 24 hours at baseline, 2 hours, 4 hours, 8 hours, 12 hours, 16 hours, 20 hours, & 24 hours.;Any adverse drug reaction between the groups. Timepoint: any complications after delivery and application of patch till 24 hours postoperatively.

—

Countries

India

Contacts

Public ContactRahul Saxena

GMC haldwani

rahul.cool.1877@gmail.com9997456219

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Apr 4, 2026