Study of low intensity pulsed ultrasound on root changes during orthodontic treatment in premolars planned for extraction

Effect of Low-Intensity Pulsed Ultrasound on root resorption and early healing response in premolars indicated for extraction during Orthodontic treatment: A split Mouth Clinical Study. - NIL

Status

Active, not recruiting

Phases

Phase 2

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2026/03/106045

Enrollment

Registered

2026-03-12

Start date

Unknown

Completion date

Unknown

Last updated

2026-03-30

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K088- Other specified disorders of teethand supporting structures

Interventions

Intervention1: low intensity pulsed ultrasound: A active ultrasound device will be applied for 20 minutes daily on the contralateral study side during the active phase of routine orthodontic treatment

Eligibility

Inclusion criteria

Inclusion criteria: Inclusion Criteria 1 Age 18years to 30 years 2 Patients indicated for extraction of all first premolars 3 Healthy periodontium and intact root morphology 4 No prior orthodontic treatment 5 Good oral hygiene and systemic health

Exclusion criteria

Exclusion criteria: Exclusion Criteria 1 Systemic diseases or drugs affecting bone metabolism 2 History of dental trauma or periapical pathology on study teeth 3 Pregnancy or lactation

Design outcomes

Primary

Measure	Time frame
Net volumetric change in root surface resorption craters (mm ) during active force application and early biological response phase between intervention and control sides. Timepoint: Baseline, 4 weeks, and 8 weeks	—

Secondary

Measure	Time frame
Correlation between coded quantitative root surface measurements and gingival crevicular fluid biomarker trends Timepoint: 4 weeks and 8 weeks.	—

Countries

India

Contacts

Public ContactDr Tejas Rajan Pol

Dr. G. D. Pol Dental College and Hospital PG Institute

tejaspol21@gmail.com9960499751

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Apr 4, 2026