To study the effect of adding injection azithromycin to standard antibiotics before a cesarean section on decreasing the risk of infection after a cesarean section.

To study azithromycin as an adjunct to standard antibiotic prophylaxis in cesarean section to further reduce the risk of post operative infection - NIL

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2026/03/106024

Enrollment

358

Registered

2026-03-12

Start date

Unknown

Completion date

Unknown

Last updated

2026-03-30

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

Intervention1: Injection Azithromycin along with injection cefazolin: Injection Azithromycin 500mg iv infusion in 250 ml saline 30-60 minutes prior to skin incision along with injection cefazolin 2gm

Eligibility

Inclusion criteria

Inclusion criteria: Women with singleton pregnancy undergoing caesarean section at term. BMI less than 30kg per meter square. Surgery lasting for less than 3 hours.

Exclusion criteria

Exclusion criteria: Patients with systemic diseases- Diabetes mellitus, hypertension, HIV,Coagulation disorder, hepatic or renal dysfunction, severe anaemia. Postpartum haemorrhage clinically evident or blood loss more than 1000ml per operatively. Women with fever or other evidence of infections prior to surgery. Prolonged rupture of membranes for more than 18 hours or chorioamnionitis. Women who are already on antibiotics. Known sensitivity to azithromycin.

Design outcomes

Primary

Measure	Time frame
Incidence of infection in postoperative patients in study group and control group.Timepoint: at baseline and 10 days post-operatively	—

Secondary

Measure	Time frame
To compare total duration of hospital stay in both groupsTimepoint: Baseline to end of study period	—

Countries

India

Contacts

Public ContactAyasha

Jawaharlal Nehru Medical College

drzehram@gmail.com9897325625

Outcome results