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A comparative study which aims to compare two differently acting anaesthetic drugs in how they effect the respiratory diaphragm function when used as anaesthetic blocks for forearm surgeries - a randomised control trail

Comparison of Levobupivacaine and Ropivacaine on Diaphragmatic function in patients undergoing Forearm surgeries under ultrasound guided Supraclavicular Brachial Plexus Block - a randomised control trial - NIL

Status
Active, not recruiting
Phases
Phase 3Phase 4
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2026/03/106006
Enrollment
182
Registered
2026-03-12
Start date
Unknown
Completion date
Unknown
Last updated
2026-03-30

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: M968- Other intraoperative and postprocedural complications and disorders of musculoskeletal system, not elsewhere classified

Interventions

Intervention1: Levobupivacaine administration: 0.375% Levobupivacaine that is 15 mL of 0.5% Levobupivacaine inn+ 5ml of NS is administered Control Intervention1: Ropivacaine: 0.375% Ropivacaine that i

Sponsors

Vemulapalli Meghana
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1) ASA Grade 1 and 2 2) Forearm Surgeries

Exclusion criteria

Exclusion criteria: 1) Patient refusal 2) Local infection 3) Bleeding disorders 4) Coagulopathies 5) Allergic to local anesthetic agent 6) Patients with neuromuscular disorders and weakness and hemidiaphragmatic dysfunction 7) Patients with pre-existing cardiac and lung pathologies 8) Pregnancy

Design outcomes

Primary

MeasureTime frame
The patients receiving Ropivacaine have less incidence of diaphragmatic dysfunction as compared to LevobupivacaineTimepoint: Assessment will be done at baseline, 15 minutes, 30 minutes and 2 hours after the block

Secondary

MeasureTime frame
Onset of sensory blockadeTimepoint: Assessment done at regular intervals of one minute to determine time of onset of block;Onset of motor blockadeTimepoint: Assessment done at regular intervals of one minute to determine time of onset of block;Duration of analgesiaTimepoint: Assessment done at intervals of immediate post op, at 6 hours, 12 hours, 24 hours & 48 hours post op points

Countries

India

Contacts

Public ContactVemulapalli Meghana

Nizam s Institute of Medical Sciences

drgeeta3007@yahoo.co.in9849264451

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Apr 4, 2026