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Comparison of Two Sedation Methods (Dexmedetomidine Alone vs Dexmedetomidine with Ketamine) for Awake Fibre-optic Nasal Intubation

A Comparative Study of Intravenous Dexmedetomidine Alone VS Dexmedetomidine Combined With Ketamine To Facilitate Awake Fibreoptic Nasal Intubation - Nil

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2026/03/106001
Enrollment
70
Registered
2026-03-12
Start date
Unknown
Completion date
Unknown
Last updated
2026-03-30

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O- Medical and Surgical

Interventions

Intervention1: Dexmedetomidine and Ketamine: Patient will be given a bolus of Injection Dexmedetomidine 50 micrograms intravenous over 15 minutes followed by Injection Ketamine 15 milligram intravenou

Sponsors

Peoples Hospital Bhopal
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Patients weighing 50-70 kilograms ASA Grade I and II All patients undergoing maxillofacial surgeries

Exclusion criteria

Exclusion criteria: Patients not giving consent ASA Grade III and IV Pregnancy and Lactating mothers Patient with nasal polyps or masses Carcinoma of Head and Neck Region and Similar Pathology

Design outcomes

Primary

MeasureTime frame
To assess whether use of dexmedetomidine alone or combined with ketamine provides ease of intubation.Timepoint: At baseline, two minutes after study drug, at beginning of fiberoptic bronchoscopy, after Endotracheal tube insertion into vocal cords, two minutes after nasal intubation

Secondary

MeasureTime frame
To assess whether use of dexmedetomidine alone or combined with ketamine provides better hemodynamic stability to the patientTimepoint: upto 15 minutes

Countries

India

Contacts

Public ContactUrvashi Nautiyal

People College Of Medical Sciences And Research Center

jainabhilekh@rediffmail.com9827606268

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Apr 4, 2026