A Study To Compare The Effects Of Adding Midazolam Versus Dexmedetomidine To Levobupivacaine For Spinal Anaesthesia In Patients Undergoing Surgeries Below The Navel

A Study To Compare Intrathecal Midazolam Versus Intrathecal Dexmedetomidine As Adjuvant To Hyperbaric Levobupivacaine For Intraoperative Analgesia Sedation Hemodynamic Parameters In Patient Undergoing Infraumbilical Surgeries - NIL

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2026/03/105992

Enrollment

Registered

2026-03-12

Start date

Unknown

Completion date

Unknown

Last updated

2026-03-30

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O- Medical and Surgical

Interventions

Intervention1: Intrathecal Midazolam 2mg As Adjuvant To Levobupivacaine 0.5% 2.8ml Once: Midazolam Acts on GABA A Receptor Of Substentia Gelatinosa And Prolongs Duration Of Anaelgesia Control Interven

Eligibility

Inclusion criteria

Inclusion criteria: Patients Willing To Give Informed Written Consent Patients Aged Between 18 To 60 Years Patients With ASA Grade 1 And 2 Patients Scheduled For Infraumbilical Surgeries Under Subarachnoid Block.

Exclusion criteria

Exclusion criteria: Patients Belonging to ASA Grade 3 4 5 Patients With Neurological Cardiovascular Respiratory Renal And Hepatic Derrangement Patients With History Of Hypersensitivity To Local Anaesthesia Benzodiazepines Patients Having Absolute Contraindication For Spinal Anaesthesia Pregnant Patient Undergoing Cesarian Section.

Design outcomes

Primary

Measure	Time frame
Duration Of Sensory Block 2 Segment Regression Time Duration Of AnaelgesiaTimepoint: Baseline 1min 2min 3min 5min Every 5 min Till 20min Every 10 min Till 180min Every 2hr Till 6 Hr Then every 6hrs Till 24Hrs	—

Secondary

Measure	Time frame
Hemodynamic parameters Sedation SafetyTimepoint: Baseline 1min 2min 3min 5min Every 5 min Till 20min Every 10 min Till 180min Every 2hr Till 6 Hr Then every 6hrs Till 24Hrs	—

Countries

India

Contacts

Public ContactDr Chiranthkumar G Nelogal

Banglore Medical College And Research Institute,

chiranth.nelogal@gmail.com9686325147

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Apr 4, 2026