Effect of local Teriparatide on the quality of new bone following extraction of mandibular posterior teeth

Effect of local Teriparatide on altering the quality of regenerated bone following extraction of mandibular posterior teeth : A triple blinded randomized controlled study - NIL

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2026/03/105979

Enrollment

Registered

2026-03-12

Start date

Unknown

Completion date

Unknown

Last updated

2026-03-30

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K029- Dental caries, unspecified

Interventions

Intervention1: Teriparatide: Collagen plug soaked in single dose of teriparatide placed in extraction socket Evaluated after 3 months Control Intervention1: Ringers Lactate: Collagen plug soaked in Ri

Eligibility

Inclusion criteria

Inclusion criteria: Patients above the age of 18 Patients requiring extraction of mandibular posterior teeth and rehabilitation with implants Patient must be willing to consent to participate in the study

Exclusion criteria

Exclusion criteria: Uncontrolled systemic disease (ASA 3, 4, 5 and 6) Any disease or drug that affects bone metabolism Patients who have undergone radiotherapy Patients having coagulation disorders Heavy smoking ( greater than 1 pack per day), drug or alcohol users Pregnant and lactating women

Design outcomes

Primary

Measure	Time frame
To compare bone quality of mandibular posterior extraction sites with and without local teriparatide, using CBCT and histological analysis Timepoint: Baseline, 3 months	—

Secondary

Measure	Time frame
To check the effect of Teriparatide on the osseointegration of implants placed in the extraction sitesTimepoint: 3 months	—

Countries

India

Contacts

Public ContactDr Pearlcid Siroraj

Sri Ramachandra Institute of Higher Education and Research

d0223004@sriher.edu.in9108286853

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Apr 4, 2026