Skip to content

Randomised control study between fentanyl , clonidine and combination of both fentanyl and clonidine as adjuvants to intrathecal hyperbaric bupivacaine for postoperative analgesia in infra umbilical surgeries

Comparison between fentanyl and clonidine and combination of both fentanyl and clonidine as adjuncts to intrathecal hyperbaric bupivacaine for postoperative analgesia in infra umbilical surgeries - Nil

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2026/03/105916
Enrollment
90
Registered
2026-03-11
Start date
Unknown
Completion date
Unknown
Last updated
2026-03-30

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: N201- Calculus of ureter

Interventions

Intervention1: Clonidine: Inj. Bupivacaine (15mg) + Clonidine (30mcg) + Distilled water (0.2ml) Single intervention , Intervention2: Fentanyl: Inj. Bupivacaine (15mg) + Fentanyl (25mcg) + Distilled

Sponsors

JSS academy of higher education and research center
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: ASAPS 1&2 Lower abdominal surgery

Exclusion criteria

Exclusion criteria: 1Patients with known comorbidities like hypertension, diabetes mellitus,epilepsy 2ASA physical status of III and IV 3.Patient having history of allergy to drug 4spinal deformity or active infection on back Psychiatric illness; Head injury; Any contraindication to spinal anaesthesia.

Design outcomes

Primary

MeasureTime frame
The present study will help to assess whether, the combination of fentanyl and clonidine with bupivacaine, will provide better analgesia, thereby improving postoperative pain relief and providing better patient satisfactionTimepoint: Time of Onset of sensory blockade Time for maximum sensory block - observed intraoperatively Post op Assessed at every hour for first four hours and every 2 hours for 20 hours

Secondary

MeasureTime frame
Onset of sensory block After spinal anaesthesia administrationTimepoint: monitored postoperatively every hour for first four hours & every 2 hours for 20 hours

Countries

India

Contacts

Public ContactDr Urlagaddala Himabindu

JSS medical college and hospital

dr.babu77@gmail.com9071295566

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Apr 4, 2026