Effect of root canal irrigants on post operative pain after root canal treatment.

Comparative evaluation of the effect of Hydroxyethylidene bisphosphonate (HEBP)-Sodium hypochlorite and neem leaf extract as root canal irrigants on post operative pain in symptomatic irreversible pulpitis: A Randomized Controlled Trial. - NIL

Status

Active, not recruiting

Phases

Phase 3Phase 4

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2026/03/105830

Enrollment

Registered

2026-03-10

Start date

Unknown

Completion date

Unknown

Last updated

2026-03-30

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K040- Pulpitis

Interventions

None listed

Eligibility

Inclusion criteria

Inclusion criteria: 1.Patients requiring endodontic therapy of mandibular molars teeth diagnosed with symptomatic irreversible pulpitis with or without associated apical periodontitis 2.Systemically healthy patients presenting with moderate to severe pain, with a Visual Analog Scale (VAS) score ranging from 3 to 10 (on a 0 10 scale) 3.Systemicallly healthy patients aged between 18 and 55 years who provided written informed consent. 4.Teeth exhibiting tenderness on percussion but without well-defined periapical radiographic changes.

Exclusion criteria

Exclusion criteria: 1.Medically compromised patients. 2.Teeth exhibiting clearly defined periapical radiolucency, calcified root canals, associated with a sinus tract and periapical abscess. 3.Teeth with incomplete apex formation 4.Patients under analgesic medication at the time of assessment. 5.Patient on antibiotic therapy. 6.Pregnant or lactating patients. 7.Patients failure to report for follow-up visits. 8.Patients unable to comply with post-operative pain assessment protocols (e.g., incomplete VAS records).

Design outcomes

Primary

Measure	Time frame
Post operative pain measurement after endodontic treatment using Numeric Rating scale.Timepoint: 6Hrs, 24Hrs, 48Hrs	—

Secondary

Measure	Time frame
NILTimepoint: NIL	—

Countries

India

Contacts

Public ContactAvishkar Dhanraj Patil

Swargiya Dadasaheb Kalmegh Smruti Dental College and Hospital Hingna Nagpur Maharashtra

ambar.raut@sdk-dentalcollege.edu.in7757805056

Outcome results