synergistic role of probiotics with antibiotics in CKD patients.

Exploring the synergistic role of probiotics with antibiotics in treating Urinary Tract Infections [UTI] among CKD patients. - nil

Status

Active, not recruiting

Phases

Phase 2

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2026/03/105829

Enrollment

180

Registered

2026-03-10

Start date

Unknown

Completion date

Unknown

Last updated

2026-03-30

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: N183- Chronic kidney disease, stage 3 (moderate)

Interventions

Intervention1: Probiotics: Probiotics Lactobacillus rhamnosusGG 2 capsules per day for 14 days Control Intervention1: Antibiotics: Tab.cefpodoxime 200 mg BD Tab. Nitrofurantoin 100 mg BD Control Inter

Eligibility

Inclusion criteria

Inclusion criteria: CKD Stage 3 or 4 patients with UTI confirmed by urine culture. Willing to participate and give informed consent.

Exclusion criteria

Exclusion criteria: Immunocompromised patients (e.g., HIV, transplant), pregnancy, lactation, prior probiotic/antibiotic use in the last month, or drug allergy

Design outcomes

Primary

Measure	Time frame
Primary: Clinical and microbiological cure at Day 14. Secondary: Recurrence at 3 months and antibiotic-related side effects.Timepoint: Primary: Clinical and microbiological cure at Day 14. Secondary: Recurrence at 3 months and antibiotic-related side effects.	—

Secondary

Measure	Time frame
Secondary: Recurrence at 3 months & antibiotic-related side effects.Timepoint: 13 weeks	—

Countries

India

Contacts

Public ContactDR velarul

Dhanalakshmi srinivasan institute of medical science and hospital

lakshmipearl.86@gmail.com8248342243

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Apr 4, 2026