Comparative Efficacy of Topical versus Systemic Corticosteroids on the Reduction of Ethmoidal Polyp Size in Patients with Chronic Rhinosinusitis: A Prospective Observational Study

A comparative study of topical and systemic steroid in ethmoidal polyposis in rural population - NIL

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2026/03/105807

Enrollment

Registered

2026-03-10

Start date

Unknown

Completion date

Unknown

Last updated

2026-03-30

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: J330- Polyp of nasal cavity

Interventions

Intervention1: Nil: Nil Intervention2: steroid nasal spray: A continuous, standard-dose course of topical corticosteroid therapy. Intervention3: oral and topical steroids combined: A short, tapering c

Eligibility

Inclusion criteria

Inclusion criteria: Patients diagnosed with ethmoidal polyposis of 20 to 70 years of age, regardless of gender

Exclusion criteria

Exclusion criteria: Patients below 20 years of age Patients above 70 years of age Chronic rhinosinusitis without polyp Antrochoanal polyp Any other nasal mass

Design outcomes

Primary

Measure	Time frame
A comparative evaluation of oral systemic steroids versus topical steroid nasal sprays, assessed by change in polyp size using the Lund-Kennedy Endoscopic Grading System (Score 0-3).Timepoint: Change in ethmoidal polyp size measured via the Lund-Kennedy Endoscopic Grading System (Score 0 3) from Baseline (Week 0) to the End of Study (Week 12).	—

Secondary

Measure	Time frame
NilTimepoint: Nil	—

Countries

India

Contacts

Public ContactDr P T Deshmukh

Jawaharlal Nehru Medical College, Wardha

drprasaddeshmukh1967@gmail.com9765404133

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Apr 4, 2026