Comparative Evaluation of Rasnasaptak Kwath and Simhasyadi Kwath in the Management of Gridhrasi with Special Reference to Sciatica

CLINICAL STUDY TO COMPARE THE EFFICACY OF RASNASAPTAK KWATH AND SIMHASYADI KWATH IN THE MANAGEMENT OF GRIDHRASI W.S.R. TO SCIATICA. - NIL

Status

Active, not recruiting

Phases

Phase 2Phase 3

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2026/03/105797

Enrollment

Registered

2026-03-10

Start date

Unknown

Completion date

Unknown

Last updated

2026-03-30

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: G55- Nerve root and plexus compressionsin diseases classified elsewhere

Interventions

None listed

Eligibility

Inclusion criteria

Inclusion criteria: 1. Patients showing classical symptoms and sign of Gridharsi described in ayurvedic samhitas. 2. Radiating pain along the course and distribution of sciatic nerve that is in buttock to outer border of foot. 3. SLR Test of patient positive upto 60 degree. 4. BRAGARDS SIGN - POSITIVE 1 5. Patients between the age of 18-60 years. 6. Patients from all socio-economic status. 7. Either sex.

Exclusion criteria

Exclusion criteria: a. Patients not willing. b. Pregnant and lactating mothers. c. Vas scale from 8 to 10 onward d. Infective disorders T.B.of spine, osteomyelitis, etc. e. Patients with paraplegia of lower limb. f. Fracture of spinal bones or in lower extremity bones. g. Patients having congenital anomalies with lumbosacral spine such as kyphosis, scoliosis. h. Patients having any major chronic or acute; systemic or surgical Pathology. i. Patients with deep wounds penetrating till sciatic nerve. j. Diabetes Mellitus. k. Patient below 18 yrs age and above 60 yrs age.

Design outcomes

Primary

Measure	Time frame
The primary outcome of the study will be to evaluate and compare the reduction in pain and improvement in functional mobility in patients with Gridhrasi after 45 days of treatment with Rasnasaptak Kwath and Simhasyadi Kwath. This will be assessed through changes in pain intensity using the Visual Analogue Scale (VAS) and improvement in Straight Leg Raise Test (SLR) angle and Bragard s sign, along with reduction in the classical symptom Sphik Kati Uru Janu Jangha Pada Kramat Ruja (radiating pain).Timepoint: 45 days	—

Measure

Time frame

The primary outcome of the study will be to evaluate and compare the reduction in pain and improvement in functional mobility in patients with Gridhrasi after 45 days of treatment with Rasnasaptak Kwath and Simhasyadi Kwath. This will be assessed through changes in pain intensity using the Visual Analogue Scale (VAS) and improvement in Straight Leg Raise Test (SLR) angle and Bragard s sign, along with reduction in the classical symptom Sphik Kati Uru Janu Jangha Pada Kramat Ruja (radiating pain).Timepoint: 45 days

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Secondary

Measure	Time frame
The secondary outcomes of the study will include evaluation of improvement in other clinical symptoms of Gridhrasi, such as Stambha (stiffness), Toda (pricking sensation), Spandan (muscle twitching), Gaurava (heaviness), and Aruchi (anorexia). Additionally, the study will assess the overall percentage of relief in symptoms, functional improvement during follow-up at 15th, 30th, and 45th day, and any adverse effects of the trial drugs, thereby determining the safety, cost-effectiveness, and comparative therapeutic efficacy of the two formulations.Timepoint: 45 days	—

Measure

Time frame

The secondary outcomes of the study will include evaluation of improvement in other clinical symptoms of Gridhrasi, such as Stambha (stiffness), Toda (pricking sensation), Spandan (muscle twitching), Gaurava (heaviness), and Aruchi (anorexia). Additionally, the study will assess the overall percentage of relief in symptoms, functional improvement during follow-up at 15th, 30th, and 45th day, and any adverse effects of the trial drugs, thereby determining the safety, cost-effectiveness, and comparative therapeutic efficacy of the two formulations.Timepoint: 45 days

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Countries

India

Contacts

Public ContactDr Pankaj Lomte

Dr Rajendra Gode Ayurved College Hospital and Research Center University Mardi Road Amravati 444602

prasadbaghele7511@gmail.com9766121012

Outcome results